Literature DB >> 19125625

Cascade palladium-catalyzed alkenyl aminocarbonylation/ intramolecular aryl amidation: an annulative synthesis of 2-quinolones.

Andrew C Tadd1, Ai Matsuno, Mark R Fielding, Michael C Willis.   

Abstract

Palladium-catalyzed intermolecular aminocarbonylation/intramolecular amidation cascade sequences can be used to convert a range of 2-(2-haloalkenyl)aryl halide substrates efficiently and selectively to the corresponding 2-quinolones. Delaying the introduction of the CO atmosphere allows an amination/carbonylation sequence and the preparation of an isoquinolone.

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Year:  2009        PMID： 19125625     DOI： 10.1021/ol802624e

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Metal-free transannulation reaction of indoles with nitrostyrenes: a simple practical synthesis of 3-substituted 2-quinolones.

Authors:  Alexander V Aksenov; Alexander N Smirnov; Nicolai A Aksenov; Inna V Aksenova; Liliya V Frolova; Alexander Kornienko; Igor V Magedov; Michael Rubin
Journal:  Chem Commun (Camb)       Date:  2013-10-18       Impact factor: 6.222

2.  DFT study of the per-6-amino-β-cyclodextrin as catalyst in synthesis of 2-aryl-2,3-dihydro-4-quinolones.

Authors:  Yali Wan; Xueye Wang; Na Liu
Journal:  J Mol Model       Date:  2014-08-20       Impact factor: 1.810

Review 3.  Applications of Palladium-Catalyzed C-N Cross-Coupling Reactions.

Authors:  Paula Ruiz-Castillo; Stephen L Buchwald
Journal:  Chem Rev       Date:  2016-09-30       Impact factor: 60.622

Review 4.  Recent Advances in One-Pot Modular Synthesis of 2-Quinolones.

Authors:  Wan Pyo Hong; Inji Shin; Hee Nam Lim
Journal:  Molecules       Date:  2020-11-20       Impact factor: 4.411

5.  Pd-Catalyzed Cascade Reactions of Aziridines: One-Step Access to Complex Tetracyclic Amines.

Authors:  Jonathan P Knowles; Hannah G Steeds; Maria Schwarz; Francesca Latter; Kevin I Booker-Milburn
Journal:  Org Lett       Date:  2021-06-16       Impact factor: 6.005
  5 in total

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