BACKGROUND: Acute pancreatitis has a variable natural history and in a proportion of patients is associated with severe complications and a significant risk of death. The various tools available for risk assessment in acute pancreatitis are reviewed. METHODS: Relevant medical literature from PubMed, Ovid, Embase, Web of Science and The Cochrane Library websites to May 2008 was reviewed. RESULTS AND CONCLUSION: Over the past 30 years several scoring systems have been developed to predict the severity of acute pancreatitis in the first 48-72 h. Biochemical and immunological markers, imaging modalities and novel predictive models may help identify patients at high risk of complications or death. Recently, there has been a recognition of the importance of the systemic inflammatory response syndrome and organ dysfunction.
BACKGROUND: Acute pancreatitis has a variable natural history and in a proportion of patients is associated with severe complications and a significant risk of death. The various tools available for risk assessment in acute pancreatitis are reviewed. METHODS: Relevant medical literature from PubMed, Ovid, Embase, Web of Science and The Cochrane Library websites to May 2008 was reviewed. RESULTS AND CONCLUSION: Over the past 30 years several scoring systems have been developed to predict the severity of acute pancreatitis in the first 48-72 h. Biochemical and immunological markers, imaging modalities and novel predictive models may help identify patients at high risk of complications or death. Recently, there has been a recognition of the importance of the systemic inflammatory response syndrome and organ dysfunction.
Authors: Aravind Suppiah; Deep Malde; Tameem Arab; Mazin Hamed; Victoria Allgar; Andrew M Smith; Gareth Morris-Stiff Journal: J Gastrointest Surg Date: 2013-02-01 Impact factor: 3.452
Authors: Xiao Xiao Chi; Xiao Ming Zhang; Tian Wu Chen; Wei Tang; Bo Xiao; Yi Fan Ji; Xiao Hua Huang Journal: Biomed Res Int Date: 2014-07-20 Impact factor: 3.411