Literature DB >> 19125378

Pien Tze Huang, a composite Chinese traditional herbal extract, affects survival of neuroblastoma cells.

Lanhai Lü1, Maria S M Wai, David T Yew, Ying T Mak.   

Abstract

Pien Tze Huang is a popular Chinese medicine for liver diseases. In the investigations of possible effects of Pien Tze Huang on the central nervous system, we first studied the in vitro anti-cancer activity of Pien Tze Huang on neuroblastoma cells (SH-SY5Y) as compared with normal fibroblasts (NIH-3T3). Results showed that Pien Tze Huang significantly decreased (p < .05) cell survival of SH-SY5Y as compared to NIH-3T3. Furthermore, the decreases in cell survival of SH-SY5Y were significantly and linearly dose-dependent (p < .05) from 400 to 1,000 microg/ml. This supports further in vivo and animal studies for anti-cancer effect, neuroprotection, and their mechanisms.

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Year:  2009        PMID： 19125378     DOI： 10.1080/00207450802324770

Source DB:  PubMed          Journal:  Int J Neurosci        ISSN： 0020-7454            Impact factor:   2.292


  8 in total

1.  Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke.

Authors:  Lihong Zhang; Wai Ping Lam; Lanhai Lü; Chunmei Wang; Yeuk Wa Wong; Lok Hang Lam; Hong Chai Tang; Maria Sen Mun Wai; Mingwei Wang; Wing Hang Kwong; Sai Ming Ngai; Ying Tat Mak; David Tai Wai Yew
Journal:  Chin Med       Date:  2010-10-18       Impact factor: 5.455

Review 2.  Recent Progress of Research on Herbal Products Used in Traditional Chinese Medicine: the Herbs belonging to The Divine Husbandman's Herbal Foundation Canon ( Shén Nóng Běn Cǎo Jīng).

Authors:  Kuo-Hsiung Lee; Susan Morris-Natschke; Keduo Qian; Yizhou Dong; Xiaoming Yang; Ting Zhou; Eileen Belding; Shou-Fang Wu; Koji Wada; Toshiyuki Akiyama
Journal:  J Tradit Complement Med       Date:  2012-01

3.  Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling.

Authors:  Li Li; Jin-Xia Sun; Xiao-Qi Wang; Xiao-Kai Liu; Xian-Xiong Chen; Bo Zhang; Zhen-Dan He; Dong-Zhou Liu; Li-Xin Chen; Li-Wei Wang; Zhong Huang
Journal:  Oncotarget       Date:  2017-11-27

4.  Therapeutic Potential of Pien Tze Huang on Experimental Autoimmune Encephalomyelitis Rat.

Authors:  Xuemei Qiu; Hui Luo; Xue Liu; Qingqing Guo; Kang Zheng; Danping Fan; Jiawen Shen; Cheng Lu; Xiaojuan He; Ge Zhang; Aiping Lu
Journal:  J Immunol Res       Date:  2018-02-27       Impact factor: 4.818

5.  Nardostachys jatamansi Root Extract Modulates the Growth of IMR-32 and SK-N-MC Neuroblastoma Cell Lines Through MYCN Mediated Regulation of MDM2 and p53.

Authors:  Snehal Suryavanshi; Prerna Raina; Rashmi Deshpande; Ruchika Kaul-Ghanekar
Journal:  Pharmacogn Mag       Date:  2017 Jan-Mar       Impact factor: 1.085

6.  Pien Tze Huang Alleviates Relapsing-Remitting Experimental Autoimmune Encephalomyelitis Mice by Regulating Th1 and Th17 Cells.

Authors:  Xuemei Qiu; Qingqing Guo; Xue Liu; Hui Luo; Danping Fan; Yongqi Deng; Hua Cui; Cheng Lu; Ge Zhang; Xiaojuan He; Aiping Lu
Journal:  Front Pharmacol       Date:  2018-10-31       Impact factor: 5.810

Review 7.  Pien Tze Huang (PZH) as a Multifunction Medicinal Agent in Traditional Chinese Medicine (TCM): a review on cellular, molecular and physiological mechanisms.

Authors:  Zhiliang Chen
Journal:  Cancer Cell Int       Date:  2021-03-03       Impact factor: 5.722

Review 8.  Therapeutic Potential of Pien-Tze-Huang: A Review on Its Chemical Composition, Pharmacology, and Clinical Application.

Authors:  Lili Huang; Yiping Zhang; Xiaoqin Zhang; Xiuping Chen; Yitao Wang; Jinjian Lu; Mingqing Huang
Journal:  Molecules       Date:  2019-09-09       Impact factor: 4.411
  8 in total

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