Endothelial dysfunction: a potential tool in gender related cardiovascular disease.

The overwhelming importance of distinctive cardiovascular disease profile in women has stimulated enormous efforts to disclose its cause. In this review, we discuss vascular endothelium as a potential phenotypic marker for the genetic difference. As it is a potentially modifiable factor for cardiovascular disease, every effort should be made to detect it, either directly or indirectly, at the earliest in females who are at risk, so that the future cardiovascular events might be prevented.