Boudewijn Van Houdenhove1, Patrick Luyten. 1. Dienst Liaisonpsychiatrie, UZ Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium. boudewijn.vanhoudenhove@uz.kuleuven.ac.be
Abstract
BACKGROUND: Syndromes characterized by chronic, medically unexplained fatigue, effort- and stress-intolerance, and widespread pain are highly prevalent in medicine. RESULTS: In chronic fatigue syndrome (CFS) and fibromyalgia (FM), various perpetuating factors may impair patients' quality of life and functioning and impede recovery. Although cognitive-behavioral and graded-exercise therapy are evidence-based treatments, the effectiveness and acceptability of therapeutic interventions in CFS/FM may largely depend on a customized approach taking the heterogeneity of perpetuating factors into account. CONCLUSION: Further research should clarify the aim and outcome of different treatment strategies in CFS/FM, as well as the underlying mechanisms of change, including those facilitating neurobiological recovery.
BACKGROUND: Syndromes characterized by chronic, medically unexplained fatigue, effort- and stress-intolerance, and widespread pain are highly prevalent in medicine. RESULTS: In chronic fatigue syndrome (CFS) and fibromyalgia (FM), various perpetuating factors may impair patients' quality of life and functioning and impede recovery. Although cognitive-behavioral and graded-exercise therapy are evidence-based treatments, the effectiveness and acceptability of therapeutic interventions in CFS/FM may largely depend on a customized approach taking the heterogeneity of perpetuating factors into account. CONCLUSION: Further research should clarify the aim and outcome of different treatment strategies in CFS/FM, as well as the underlying mechanisms of change, including those facilitating neurobiological recovery.
Authors: Stefan Kempke; Patrick Luyten; Boudewijn Van Houdenhove; Lutgarde Goossens; Patrick Bekaert; Peter Van Wambeke Journal: Clin Rheumatol Date: 2011-05-17 Impact factor: 2.980
Authors: Patrick Luyten; Boudewijn Van Houdenhove; Chi-Un Pae; Stefan Kempke; Peter Van Wambeke Journal: Psychiatry Investig Date: 2008-12-31 Impact factor: 2.505
Authors: Hanneke Kalisvaart; Saskia van Broeckhuysen; Martina Bühring; Marianne B Kool; Sandra van Dulmen; Rinie Geenen Journal: PLoS One Date: 2012-08-14 Impact factor: 3.240