Literature DB >> 19121938

Preliminary investigations on the synthesis and antitumor activity of 3(2H)-furanones.

J P Rappai1, V Raman, P A Unnikrishnan, S Prathapan, S K Thomas, C S Paulose.   

Abstract

Two triaryl-3(2H)-furanones were synthesized and their antitumor activity was evaluated. These compounds inhibited the proliferation of DLA cell line in vitro. In vivo studies also showed that these compounds were active against tumor cell proliferation.

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Year:  2008        PMID: 19121938     DOI: 10.1016/j.bmcl.2008.12.030

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  5-(Biphenyl-4-yl)-3-(3-meth-oxy-benzyl-idene)furan-2(3H)-one.

Authors:  Jerry P Jasinski; James A Golen; A S Dayananda; H S Yathirajan; Ravinesh Mishra
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-08-11
  1 in total

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