Literature DB >> 19121599

An accidental case of aconite poisoning due to Kampo herbal medicine ingestion.

Takiyoshi Ono1, Makiko Hayashida, Kyoko Uekusa, Cui Fan Lai, Hideyuki Hayakawa, Makoto Nihira, Youkichi Ohno.   

Abstract

An accidental case of aconite intoxication occurred after a patient took a therapeutic dose of Kampo herbal medicine containing Aconiti tuber, Uzu but had used the wrong decoction procedure. The poisoning was likely caused by an increased level of Aconitum alkaloids in the decoction; the patient developed aconite intoxication due to incomplete decoction. Aconitum alkaloid levels in the leftover solution which the patient had drunk and in the decoction extracted from 3g Uzu were determined. It was found that decoction makes the medicine safer to drink. Older individuals, especially those with dementia, have a higher risk of aconite poisoning because they sometimes do not boil the medicine appropriately.

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Year:  2009        PMID: 19121599     DOI: 10.1016/j.legalmed.2008.11.001

Source DB:  PubMed          Journal:  Leg Med (Tokyo)        ISSN: 1344-6223            Impact factor:   1.376


  5 in total

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Authors:  Valerio Mezzasalma; Ioannis Ganopoulos; Andrea Galimberti; Laura Cornara; Emanuele Ferri; Massimo Labra
Journal:  Int J Legal Med       Date:  2016-10-30       Impact factor: 2.686

2.  Quantitative Assessment of the Influence of Rhizoma Zingiberis on the Level of Aconitine in Rat Gut Sacs and Qualitative Analysis of the Major Influencing Components of Rhizoma Zingiberis on Aconitine Using UPLC/MS.

Authors:  Yang Xin; Shuying Liu
Journal:  PLoS One       Date:  2015-05-15       Impact factor: 3.240

3.  Identification of crude drugs in the Japanese pharmacopoeia using a DNA barcoding system.

Authors:  Xiaochen Chen; Li Xiang; Linchun Shi; Gang Li; Hui Yao; Jianping Han; Yulin Lin; Jingyuan Song; Shilin Chen
Journal:  Sci Rep       Date:  2017-02-10       Impact factor: 4.379

Review 4.  Toxicity of herbal medications suggested as treatment for COVID-19: A narrative review.

Authors:  Michael A DiPietro; Christopher Mondie
Journal:  J Am Coll Emerg Physicians Open       Date:  2021-03-31

5.  Quantitative and Qualitative Analysis of Aconitum Alkaloids in Raw and Processed Chuanwu and Caowu by HPLC in Combination with Automated Analytical System and ESI/MS/MS.

Authors:  Aimin Sun; Bo Gao; Xueqing Ding; Chi-Ming Huang; Paul Pui-Hay But
Journal:  J Anal Methods Chem       Date:  2012-04-11       Impact factor: 2.193

  5 in total

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