| Literature DB >> 19121550 |
Gamal A Idrees1, Gamal el-Din A Abuo-Rahma, Omar M Aly, Mohamed F Radwan.
Abstract
Novel 2-substituted isobutyric acid derivatives were synthesized and their hypolipidemic activity was evaluated in high cholesterol diet fed rat model. The amide 5a was found to decrease the levels of serum total cholesterol, LDL cholesterol and triglycerides in hyperlipidemic rats to a greater degree than the reference gemfibrozil.Entities:
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Year: 2008 PMID： 19121550 DOI： 10.1016/j.ejmech.2008.12.009
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514