Literature DB >> 19120101

Central neuropeptide Y in anxiety- and stress-related behavior and in ethanol intake.

Annika Thorsell1.   

Abstract

One of the most profound properties of central neuropeptide Y (NPY) is its anxiolytic, or anti-anxiety, effect. This has been demonstrated repeatedly in a number of animal models. In addition, stressors affect NPY expression in the central nervous system, with acute and repeated (chronic) stress having differential effects. Here, a brief summary of some work performed in our laboratory is presented that supports a role for NPY in regulation of stress responses and behaviors.

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Year:  2008        PMID： 19120101     DOI： 10.1196/annals.1410.083

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  13 in total

1.  Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.

Authors:  Wolfgang H Sommer; Jessica Lidström; Hui Sun; Derek Passer; Robert Eskay; Stephen C J Parker; Stephanie H Witt; Ulrich S Zimmermann; Vanessa Nieratschker; Marcella Rietschel; Elliott H Margulies; Miklós Palkovits; Manfred Laucht; Markus Heilig
Journal:  Hum Mutat       Date:  2010-08       Impact factor: 4.878

Review 2.  Synaptic effects induced by alcohol.

Authors:  David M Lovinger; Marisa Roberto
Journal:  Curr Top Behav Neurosci       Date:  2013

Review 3.  Pathophysiology of Migraine: A Disorder of Sensory Processing.

Authors:  Peter J Goadsby; Philip R Holland; Margarida Martins-Oliveira; Jan Hoffmann; Christoph Schankin; Simon Akerman
Journal:  Physiol Rev       Date:  2017-04       Impact factor: 37.312

4.  Opposite effects on the ingestion of ethanol and sucrose solutions after injections of muscimol into the nucleus accumbens shell.

Authors:  Thomas R Stratford; David Wirtshafter
Journal:  Behav Brain Res       Date:  2010-09-08       Impact factor: 3.332

Review 5.  Influence of stress associated with chronic alcohol exposure on drinking.

Authors:  Howard C Becker
Journal:  Neuropharmacology       Date:  2017-04-19       Impact factor: 5.250

6.  A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.

Authors:  Philippa Mitchell; Richard Mould; James Dillon; Steven Glautier; Ioannis Andrianakis; Christopher James; Amanda Pugh; Lindy Holden-Dye; Vincent O'Connor
Journal:  PLoS One       Date:  2010-05-03       Impact factor: 3.240

7.  Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight.

Authors:  Bin Qiu; Richard L Bell; Yong Cao; Lingling Zhang; Robert B Stewart; Tamara Graves; Lawrence Lumeng; Weidong Yong; Tiebing Liang
Journal:  J Genet Genomics       Date:  2016-04-29       Impact factor: 4.275

Review 8.  Neuroscience of alcoholism: molecular and cellular mechanisms.

Authors:  Sachin Moonat; Bela G Starkman; Amul Sakharkar; Subhash C Pandey
Journal:  Cell Mol Life Sci       Date:  2009-09-10       Impact factor: 9.261

Review 9.  Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience.

Authors:  John H Krystal; Alexander Neumeister
Journal:  Brain Res       Date:  2009-03-28       Impact factor: 3.252

10.  Attenuated stress-evoked anxiety, increased sucrose preference and delayed spatial learning in glucocorticoid-induced receptor-deficient mice.

Authors:  L E Vollmer; S Ghosal; J A Rush; F R Sallee; J P Herman; M Weinert; R Sah
Journal:  Genes Brain Behav       Date:  2012-11-27       Impact factor: 3.449
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