| Literature DB >> 1911984 |
A Balbi1, E Sottofattori, M Mazzei, W G Sannita.
Abstract
The in vivo bioavailability of magnesium valproate (500 and 1000 mg) enteric-coated tablets has been compared with that of sodium valproate (Depakine) (500 and 1000 mg) enteric-coated tablets. The two preparations were found to be bioequivalent; magnesium valproate appeared to be a drug without bioavailability problems and with reduced inter-subject variability, compared with that of sodium valproate. A reversed-phase HPLC method for the determination of valproates is described.Entities:
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Year: 1991 PMID： 1911984 DOI： 10.1016/0731-7085(91)80200-s
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935