Literature DB >> 19118475

Management of renal masses with laparoscopic-guided radiofrequency ablation versus laparoscopic partial nephrectomy.

Vincent G Bird1, Robert I Carey, Rajinikanth Ayyathurai, Victoria Y Bird.   

Abstract

BACKGROUND AND
PURPOSE: Laparoscopic-guided radiofrequency ablation (LRFA) has been introduced as a minimally invasive nephron-sparing management option for renal tumors. Many patients who desire treatment present with multiple comorbidities, which poses a therapeutic challenge. Our purpose is to determine if multipass LRFA is comparable, in terms of surgical risk and immediate postoperative outcomes, to laparoscopic partial nephrectomy (LPN). PATIENTS AND METHODS: A retrospective study identified 36 and 33 patients who underwent LRFA and LPN, respectively. Perioperative demographic data, tumor characteristics, and follow-up data were evaluated. Statistical analysis was performed using the Student t test and chi-square analysis.
RESULTS: Age, American Society of Anesthesiology score, and Charlson Comorbidity Index were significantly higher in the LRFA group than the LPN group (P < 0.001). Average tumor size was 2.8 cm and 3.1 cm for the LRFA and LPN groups, respectively. There were no significant differences in change between the preoperative and postoperative creatinine/glomerular filtration rate values or perioperative complication rates for the groups. Estimated blood loss and length of stay were significantly lower for the LRFA group than the LPN group (P < 0.05). Follow-up ranged 6 to 23 months and 6 to 58 months for the LRFA and the LPN groups, respectively. There has been no evidence of tumor recurrence in the follow-up period.
CONCLUSIONS: We present our initial report comparing patients undergoing LRFA v LPN for the management of renal tumors. Our preliminary results with our experience with multipass laparoscopic-guided RFA demonstrate that this technique can be safely used in an elderly, higher risk population. Long-term follow-up is needed to determine oncologic efficacy.

Entities:  

Mesh:

Year:  2009        PMID: 19118475     DOI: 10.1089/end.2008.0087

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  8 in total

1.  Outcome of radiofrequency ablation over partial nephrectomy for small renal mass (<4 cm): a systematic review and meta-analysis.

Authors:  Yue Yang; Shouzhen Chen; Fan Chen; Kejia Zhu; Qiming Deng; Li Luo; Benkang Shi
Journal:  Int J Clin Exp Med       Date:  2015-11-15

Review 2.  Laparoscopic and image-guided radiofrequency ablation of renal tumors: patient selection and outcomes.

Authors:  Scott M Castle; Vladislav Gorbatiy; Obi Ekwenna; Raymond J Leveillee
Journal:  Curr Urol Rep       Date:  2011-04       Impact factor: 3.092

3.  A Systematic Review and Meta-Analysis of Minimally Invasive Partial Nephrectomy Versus Focal Therapy for Small Renal Masses.

Authors:  Lin Dong; Wang You Liang; Lu Ya; Liu Yang; Wei Qiang
Journal:  Front Oncol       Date:  2022-05-26       Impact factor: 5.738

4.  Ten-year experience of percutaneous image-guided radiofrequency ablation of malignant renal tumours in high-risk patients.

Authors:  P Balageas; F Cornelis; Y Le Bras; R Hubrecht; J C Bernhard; J M Ferrière; A Ravaud; N Grenier
Journal:  Eur Radiol       Date:  2013-02-27       Impact factor: 5.315

Review 5.  Ablative therapies for small renal tumours.

Authors:  Arturo Castro; Lawrence C Jenkins; Nelson Salas; Gideon Lorber; Raymond J Leveillee
Journal:  Nat Rev Urol       Date:  2013-04-23       Impact factor: 14.432

6.  Partial nephrectomy versus ablative techniques for small renal masses: a systematic review and network meta-analysis.

Authors:  Johannes Uhlig; Arne Strauss; Gerta Rücker; Ali Seif Amir Hosseini; Joachim Lotz; Lutz Trojan; Hyun S Kim; Annemarie Uhlig
Journal:  Eur Radiol       Date:  2018-09-25       Impact factor: 5.315

7.  Current and future technology for minimally invasive ablation of renal cell carcinoma.

Authors:  Branden G Duffey; J Kyle Anderson
Journal:  Indian J Urol       Date:  2010-07

Review 8.  Radiofrequency Ablation Versus Partial Nephrectomy in Treating Small Renal Tumors: A Systematic Review and Meta-Analysis.

Authors:  Xiaotao Yin; Liang Cui; Fanglong Li; Siyong Qi; Zhaoyang Yin; Jiangping Gao
Journal:  Medicine (Baltimore)       Date:  2015-12       Impact factor: 1.817

  8 in total

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