PURPOSE: To assess the prevalence and variation of post-concussion symptoms within the first year after mild traumatic brain injury (TBI), and explore the association between injury severity, demographic factors and symptoms. METHODS: Prospective study of patients with mild TBI followed up at 3, 6 and 12 months (N= 96 included, n = 52 attending all follow-ups). Sociodemographic factors, injury mechanisms and impact of injury (Glasgow Coma Scale score, Abbreviated Injury Severity Score (AIS), Injury Severity Score) were recorded at inclusion. Symptoms were reported in the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) at the follow-ups. The sumscore of all symptoms in RPQ was calculated for each subject. Scores were also calculated separately for the cognitive, physical and behavioural symptoms. RESULTS: Twenty-nine subjects met the post-concussion syndrome criteria at 3 months, and 22 patients at 6 and 12 months. The cognitive symptoms were more prominent than the physical and behavioural symptoms. The cognitive and physical symptoms were associated with AIS for the head injury at 3 months, but not at 12 months. Considerable individual variability in the symptom pattern was found, and the subjects who attended only the 3-months follow-up reported a lower level of symptoms than those attending all follow-ups. CONCLUSIONS: Persistence of symptoms was a considerable problem even 1 year after the injury, with cognitive symptoms dominating. More severe AIS scores were associated with a higher level of cognitive and physical symptoms at 3 months, but not at later follow-ups. Strategies to prevent and treat these symptoms should be focussed in clinical practice.
PURPOSE: To assess the prevalence and variation of post-concussion symptoms within the first year after mild traumatic brain injury (TBI), and explore the association between injury severity, demographic factors and symptoms. METHODS: Prospective study of patients with mild TBI followed up at 3, 6 and 12 months (N= 96 included, n = 52 attending all follow-ups). Sociodemographic factors, injury mechanisms and impact of injury (Glasgow Coma Scale score, Abbreviated Injury Severity Score (AIS), Injury Severity Score) were recorded at inclusion. Symptoms were reported in the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) at the follow-ups. The sumscore of all symptoms in RPQ was calculated for each subject. Scores were also calculated separately for the cognitive, physical and behavioural symptoms. RESULTS: Twenty-nine subjects met the post-concussion syndrome criteria at 3 months, and 22 patients at 6 and 12 months. The cognitive symptoms were more prominent than the physical and behavioural symptoms. The cognitive and physical symptoms were associated with AIS for the head injury at 3 months, but not at 12 months. Considerable individual variability in the symptom pattern was found, and the subjects who attended only the 3-months follow-up reported a lower level of symptoms than those attending all follow-ups. CONCLUSIONS: Persistence of symptoms was a considerable problem even 1 year after the injury, with cognitive symptoms dominating. More severe AIS scores were associated with a higher level of cognitive and physical symptoms at 3 months, but not at later follow-ups. Strategies to prevent and treat these symptoms should be focussed in clinical practice.
Authors: Danielle N Lyons; Hemendra Vekaria; Teresa Macheda; Vikas Bakshi; David K Powell; Brian T Gold; Ai-Ling Lin; Patrick G Sullivan; Adam D Bachstetter Journal: J Neurotrauma Date: 2018-07-02 Impact factor: 5.269
Authors: Amanda R Rabinowitz; Xiaoqi Li; Stephen R McCauley; Elisabeth A Wilde; Amanda Barnes; Gerri Hanten; Donna Mendez; James J McCarthy; Harvey S Levin Journal: J Neurotrauma Date: 2015-07-17 Impact factor: 5.269
Authors: Shervin Minaee; Yao Wang; Alp Aygar; Sohae Chung; Xiuyuan Wang; Yvonne W Lui; Els Fieremans; Steven Flanagan; Joseph Rath Journal: IEEE Trans Med Imaging Date: 2019-03-18 Impact factor: 10.048
Authors: Victoria E Johnson; Maura T Weber; Rui Xiao; D Kacy Cullen; David F Meaney; William Stewart; Douglas H Smith Journal: Acta Neuropathol Date: 2018-02-19 Impact factor: 17.088
Authors: S Chung; X Wang; E Fieremans; J F Rath; P Amorapanth; F-Y A Foo; C J Morton; D S Novikov; S R Flanagan; Y W Lui Journal: AJNR Am J Neuroradiol Date: 2019-08-01 Impact factor: 3.825