| Literature DB >> 19115972 |
Wan Beom Park1, Pyoeng Gyun Choe, Kyoung-Ho Song, Shinwon Lee, Hee-Chang Jang, Jae Hyun Jeon, Sang-Won Park, Myoung Hee Park, Myoung-don Oh, Kang Won Choe.
Abstract
Human leukocyte antigen allele (HLA)-B*5701 is associated with abacavir hypersensitivity. However, the carriage rate of HLA-B*5701 has rarely been studied in Asians. In 534 Korean patients with human immunodeficiency virus infection, HLA-B*5701 status was determined by polymerase chain reaction with HLA-B*5701-specific primers. No patients had the HLA-B*5701 allele (95% confidence interval, 0%-0.7%). This explains the paucity of immunologically confirmed cases of abacavir hypersensitivity in Koreans.Entities:
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Year: 2009 PMID： 19115972 DOI： 10.1086/595890
Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079