Literature DB >> 19114875

Bupropion-associated QRS prolongation unresponsive to sodium bicarbonate therapy.

Brandon K Wills1, Michele Zell-Kanter, Steven E Aks.   

Abstract

We describe a case of bupropion-associated QRS prolongation that was unresponsive to intravenous bolus therapy of sodium bicarbonate. Bupropion may cause seizures and conduction delays similar to tricyclic antidepressants in the overdose setting by an unknown mechanism.

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Year:  2009        PMID： 19114875     DOI： 10.1097/MJT.0b013e3180a5bd83

Source DB:  PubMed          Journal:  Am J Ther        ISSN： 1075-2765            Impact factor:   2.688


  3 in total

Review 1.  A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening.

Authors:  Rebecca E Bruccoleri; Michele M Burns
Journal:  J Med Toxicol       Date:  2016-03

2.  Successful Management of Adolescent Bupropion Overdose with Intravenous Lipid Emulsion Therapy.

Authors:  Kasha Bornstein; Tim Montrief; Mehruba Anwar Parris
Journal:  J Pediatr Intensive Care       Date:  2019-07-25

Review 3.  Drugs and pharmaceuticals: management of intoxication and antidotes.

Authors:  Silas W Smith
Journal:  EXS       Date:  2010
  3 in total

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