Diagnosis and the current trends in multiple myeloma therapy.

Multiple myeloma is still an incurable disease. In recent years the introduction of 3 novel drugs oriented on basic mechanisms of multiple myeloma cells proliferation and survival has improved patients' outcome. These drugs are: thalidomide, its new analog, lenalidomide, and proteasome inhibitor, bortezomib. All three are highly effective both in newly diagnosed and relapsed/resistant patients.