Literature DB >> 19112029

Generation of multiply charged peptides and proteins by radio frequency acoustic desorption and ionization for mass spectrometric detection.

R Brent Dixon1, Jason S Sampson, David C Muddiman.   

Abstract

The design and implementation of a radio frequency acoustic desorption ionization (RADIO) source has been demonstrated for the analysis of multiply charged peptides and proteins. One muL aliquots of melittin, BNP-32, and ubiquitin ( approximately 1 mug of analyte) were deposited onto a quartz crystal microbalance (QCM) electrode before radio frequency actuation for desorption. Continuous electrospray parallel to/above the sampling surface enabled the ionization of desorbed species. Detection by a hybrid linear ion trap Fourier transform ion cyclotron resonance mass spectrometer confirmed the intact and dissociated species observed during MS and MS/MS experiments, respectively.

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Year:  2008        PMID： 19112029     DOI： 10.1016/j.jasms.2008.11.024

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN： 1044-0305            Impact factor:   3.109


  16 in total

1.  Secondary electrospray ionization ion mobility spectrometry/mass spectrometry of illicit drugs.

Authors:  C Wu; W F Siems; H H Hill
Journal:  Anal Chem       Date:  2000-01-15       Impact factor: 6.986

2.  Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids.

Authors:  Jentaie Shiea; Min-Zon Huang; Hsiu-Jung Hsu; Chi-Yang Lee; Cheng-Hui Yuan; Iwona Beech; Jan Sunner
Journal:  Rapid Commun Mass Spectrom       Date:  2005       Impact factor: 2.419

3.  Differentiation of maturity and quality of fruit using noninvasive extractive electrospray ionization quadrupole time-of-flight mass spectrometry.

Authors:  Huanwen Chen; Yanping Sun; Arno Wortmann; Haiwei Gu; Renato Zenobi
Journal:  Anal Chem       Date:  2007-02-15       Impact factor: 6.986

4.  Direct characterization of intact polypeptides by matrix-assisted laser desorption electrospray ionization quadrupole Fourier transform ion cyclotron resonance mass spectrometry.

Authors:  Jason S Sampson; Adam M Hawkridge; David C Muddiman
Journal:  Rapid Commun Mass Spectrom       Date:  2007       Impact factor: 2.419

5.  Neutral desorption sampling coupled to extractive electrospray ionization mass spectrometry for rapid differentiation of biosamples by metabolomic fingerprinting.

Authors:  Huanwen Chen; Arno Wortmann; Renato Zenobi
Journal:  J Mass Spectrom       Date:  2007-09       Impact factor: 1.982

6.  Neutral desorption sampling of living objects for rapid analysis by extractive electrospray ionization mass spectrometry.

Authors:  Huanwen Chen; Shuiping Yang; Arno Wortmann; Renato Zenobi
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

7.  Quantitative mass spectral evidence for the absence of circulating brain natriuretic peptide (BNP-32) in severe human heart failure.

Authors:  Adam M Hawkridge; Denise M Heublein; H Robert Bergen; Alessandro Cataliotti; John C Burnett; David C Muddiman
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-17       Impact factor: 11.205

8.  Eliminating the interferences from TRIS buffer and SDS in protein analysis by fused-droplet electrospray ionization mass spectrometry.

Authors:  I-Fan Shieh; Chi-Yang Lee; Jentaie Shiea
Journal:  J Proteome Res       Date:  2005 Mar-Apr       Impact factor: 4.466

9.  Analysis of base oil fractions by ClMn(H2O)+ chemical ionization combined with laser-induced acoustic desorption/fourier transform ion cyclotron resonance mass spectrometry.

Authors:  Penggao Duan; Kuangnan Qian; Steven C Habicht; David S Pinkston; Mingkun Fu; Hilkka I Kenttämaa
Journal:  Anal Chem       Date:  2008-02-22       Impact factor: 6.986

10.  Analytical performance of a venturi-assisted array of micromachined ultrasonic electrosprays coupled to ion trap mass spectrometry for the analysis of peptides and proteins.

Authors:  Christina Y Hampton; Thomas P Forbes; Mark J Varady; J Mark Meacham; Andrei G Fedorov; F Levent Degertekin; Facundo M Fernández
Journal:  Anal Chem       Date:  2007-10-03       Impact factor: 6.986
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  7 in total

1.  Paper spray ionization of polar analytes using non-polar solvents.

Authors:  Anyin Li; He Wang; Zheng Ouyang; R Graham Cooks
Journal:  Chem Commun (Camb)       Date:  2011-02-01       Impact factor: 6.222

Review 2.  What can we learn from ambient ionization techniques?

Authors:  Huanwen Chen; Gerardo Gamez; Renato Zenobi
Journal:  J Am Soc Mass Spectrom       Date:  2009-08-13       Impact factor: 3.109

3.  Desorption in Mass Spectrometry.

Authors:  Dilshadbek Tursunbayevich Usmanov; Satoshi Ninomiya; Lee Chuin Chen; Subhrakanti Saha; Mridul Kanti Mandal; Yuji Sakai; Rio Takaishi; Ahsan Habib; Kenzo Hiraoka; Kentaro Yoshimura; Sen Takeda; Hiroshi Wada; Hiroshi Nonami
Journal:  Mass Spectrom (Tokyo)       Date:  2017-02-24

4.  Laserspray and matrix-assisted ionization inlet coupled to high-field FT-ICR mass spectrometry for peptide and protein analysis.

Authors:  Leonard Nyadong; Ellen D Inutan; Xu Wang; Christopher L Hendrickson; Sarah Trimpin; Alan G Marshall
Journal:  J Am Soc Mass Spectrom       Date:  2013-02-05       Impact factor: 3.109

5.  Desorption mass spectrometry for nonvolatile compounds using an ultrasonic cutter.

Authors:  Ahsan Habib; Satoshi Ninomiya; Lee Chuin Chen; Dilshadbek T Usmanov; Kenzo Hiraoka
Journal:  J Am Soc Mass Spectrom       Date:  2014-05-16       Impact factor: 3.109

6.  Fizzy Extraction of Volatile Organic Compounds Combined with Atmospheric Pressure Chemical Ionization Quadrupole Mass Spectrometry.

Authors:  Hao-Chun Yang; Cheng-Hao Chang; Pawel L Urban
Journal:  J Vis Exp       Date:  2017-07-14       Impact factor: 1.355

7.  Transferring Ions from Solution to the Gas Phase: The Two Basic Principles.

Authors:  Sebastiaan F Teunissen; Marcos N Eberlin
Journal:  J Am Soc Mass Spectrom       Date:  2017-08-30       Impact factor: 3.109
  7 in total

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