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Literature DB >> 19111763

Information learned from animal models of atrial fibrillation.

J Emanuel Finet¹, David S Rosenbaum, J Kevin Donahue.

Abstract

Animal models of atrial fibrillation have taught us about mechanisms of this common disease. A variety of animal models exist, including models of lone atrial fibrillation and models of atrial fibrillation in the setting of heart failure, aging, or pericardial inflammation. This article reviews these various models.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2009 PMID： 19111763 PMCID： PMC2654199 DOI： 10.1016/j.ccl.2008.09.005

Source DB: PubMed Journal: Cardiol Clin ISSN： 0733-8651 Impact factor: 2.213

50 in total

Review 1. Pathophysiology and prevention of atrial fibrillation.

Authors: M A Allessie; P A Boyden; A J Camm; A G Kléber; M J Lab; M J Legato; M R Rosen; P J Schwartz; P M Spooner; D R Van Wagoner ; A L Waldo
Journal: Circulation Date: 2001-02-06 Impact factor: 29.690

2. Cardiomyocyte remodelling during myocardial hibernation and atrial fibrillation: prelude to apoptosis.

Authors: G D Dispersyn; J Ausma; F Thoné; W Flameng; J L Vanoverschelde; M A Allessie; F C Ramaekers; M Borgers
Journal: Cardiovasc Res Date: 1999-09 Impact factor: 10.787

3. Remodeling of atrial dimensions and emptying function in canine models of atrial fibrillation.

Authors: Y Shi; A Ducharme; D Li; R Gaspo; S Nattel; J C Tardif
Journal: Cardiovasc Res Date: 2001-11 Impact factor: 10.787

4. Time course of atrial fibrillation-induced cellular structural remodeling in atria of the goat.

Authors: J Ausma; N Litjens; M H Lenders; H Duimel; F Mast; L Wouters; F Ramaekers; M Allessie; M Borgers
Journal: J Mol Cell Cardiol Date: 2001-12 Impact factor: 5.000

5. Single site radiofrequency catheter ablation of atrial fibrillation: studies guided by simultaneous multisite mapping in the canine sterile pericarditis model.

Authors: K Kumagai; K Uno; C Khrestian; A L Waldo
Journal: J Am Coll Cardiol Date: 2000-09 Impact factor: 24.094

6. Gap junctional remodeling in relation to stabilization of atrial fibrillation in the goat.

Authors: H M van der Velden; J Ausma; M B Rook; A J Hellemons; T A van Veen; M A Allessie; H J Jongsma
Journal: Cardiovasc Res Date: 2000-06 Impact factor: 10.787

7. Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs.

Authors: Kaori Shinagawa; Yan-Fen Shi; Jean-Claude Tardif; Tack-Ki Leung; Stanley Nattel
Journal: Circulation Date: 2002-06-04 Impact factor: 29.690

8. Characterization of in vivo and in vitro electrophysiological and antiarrhythmic effects of a novel IKACh blocker, NIP-151: a comparison with an IKr-blocker dofetilide.

Authors: Norio Hashimoto; Toru Yamashita; Nobutomo Tsuruzoe
Journal: J Cardiovasc Pharmacol Date: 2008-02 Impact factor: 3.105

Review 9. Therapeutic implications of atrial fibrillation mechanisms: can mechanistic insights be used to improve AF management?

Authors: Stanley Nattel
Journal: Cardiovasc Res Date: 2002-05 Impact factor: 10.787

Information learned from animal models of atrial fibrillation.

Review 1. Pathophysiology and prevention of atrial fibrillation.

2. Cardiomyocyte remodelling during myocardial hibernation and atrial fibrillation: prelude to apoptosis.

3. Remodeling of atrial dimensions and emptying function in canine models of atrial fibrillation.

4. Time course of atrial fibrillation-induced cellular structural remodeling in atria of the goat.

5. Single site radiofrequency catheter ablation of atrial fibrillation: studies guided by simultaneous multisite mapping in the canine sterile pericarditis model.

6. Gap junctional remodeling in relation to stabilization of atrial fibrillation in the goat.

7. Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs.

8. Characterization of in vivo and in vitro electrophysiological and antiarrhythmic effects of a novel IKACh blocker, NIP-151: a comparison with an IKr-blocker dofetilide.

Review 9. Therapeutic implications of atrial fibrillation mechanisms: can mechanistic insights be used to improve AF management?

10. Cellular electrophysiologic properties of old canine atria provide a substrate for arrhythmogenesis.

Review 1. Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation.

Review 2. Mechanisms of arrhythmias and conduction disorders in older adults.

3. Translatability scoring in drug development: eight case studies.

4. Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp.

5. Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes.

6. Simulation of Ectopic Pacemakers in the Heart: Multiple Ectopic Beats Generated by Reentry inside Fibrotic Regions.

Review 7. Atrial Fibrillation: The Science behind Its Defiance.