OBJECTIVE: Women with a history of preeclampsia are at increased risk for long-term cardiovascular morbidity and mortality. This study assessed whether a pregnancy complicated by preeclampsia is associated with an increased prevalence of maternal hypertension and other cardiovascular risk factors shortly after delivery. STUDY DESIGN: Seventy-nine cases and 140 controls that had been enrolled in a prospective case-control study were evaluated in this planned follow-up analysis. The presence of hypertension, diabetes and dyslipidemia were assessed by standardized questionnaire 6-13 months after delivery. RESULTS: Women with preeclampsia were significantly more likely than controls to have hypertension (adjusted odds ratio, 13.92; 95% CI, 5.17-37.4; P < .001) after adjusting for confounders. Women with preterm preeclampsia also had an increased odds of hypertension (adjusted odds ratio, 18.31; 95% CI, 5.04-66.46; P < .001) compared with controls. CONCLUSION: Pregnancy complications, such as preeclampsia, may provide opportunities to identify women at risk for cardiovascular morbidity years before the onset of disease, allowing a window for prevention and intervention.
OBJECTIVE:Women with a history of preeclampsia are at increased risk for long-term cardiovascular morbidity and mortality. This study assessed whether a pregnancy complicated by preeclampsia is associated with an increased prevalence of maternal hypertension and other cardiovascular risk factors shortly after delivery. STUDY DESIGN: Seventy-nine cases and 140 controls that had been enrolled in a prospective case-control study were evaluated in this planned follow-up analysis. The presence of hypertension, diabetes and dyslipidemia were assessed by standardized questionnaire 6-13 months after delivery. RESULTS:Women with preeclampsia were significantly more likely than controls to have hypertension (adjusted odds ratio, 13.92; 95% CI, 5.17-37.4; P < .001) after adjusting for confounders. Women with preterm preeclampsia also had an increased odds of hypertension (adjusted odds ratio, 18.31; 95% CI, 5.04-66.46; P < .001) compared with controls. CONCLUSION: Pregnancy complications, such as preeclampsia, may provide opportunities to identify women at risk for cardiovascular morbidity years before the onset of disease, allowing a window for prevention and intervention.
Authors: Morven Caroline Brown; Kate Elizabeth Best; Mark Stephen Pearce; Jason Waugh; Stephen Courtenay Robson; Ruth Bell Journal: Eur J Epidemiol Date: 2013-02-09 Impact factor: 8.082
Authors: Pensee Wu; Chun Shing Kwok; Randula Haththotuwa; Rafail A Kotronias; Aswin Babu; Anthony A Fryer; Phyo K Myint; Carolyn A Chew-Graham; Mamas A Mamas Journal: Diabetologia Date: 2016-09-19 Impact factor: 10.122
Authors: T Katrien J Groenhof; Bas B van Rijn; Arie Franx; Jeanine E Roeters van Lennep; Michiel L Bots; A Titia Lely Journal: Eur J Prev Cardiol Date: 2017-09-12 Impact factor: 7.804