Literature DB >> 19110591

Polyethylene glycol-conjugated immunoliposomes specific for olfactory ensheathing glial cells.

V P Chekhonin1, O I Gurina, O V Ykhova, A E Ryabinina, E A Tsibulkina, Yu A Zhirkov.   

Abstract

A novel immunoliposome delivery system was developed for directed transport into cultured olfactory epithelium cells. Monoclonal antibodies against glial fibrillary acidic protein (GFAP) served as a vector. Fluorescence microscopy showed that the target cells are specifically stained with Dil dye incorporated into liposomal membranes. This transport system holds promise for the delivery of bioactive substances to olfactory epithelial cells and modulation of their capacity to stimulate axonal regeneration.

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Year:  2008        PMID: 19110591     DOI: 10.1007/s10517-008-0115-5

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Inhalable PEGylated Phospholipid Nanocarriers and PEGylated Therapeutics for Respiratory Delivery as Aerosolized Colloidal Dispersions and Dry Powder Inhalers.

Authors:  Priya Muralidharan; Evan Mallory; Monica Malapit; Don Hayes; Heidi M Mansour
Journal:  Pharmaceutics       Date:  2014-06-20       Impact factor: 6.321

  1 in total

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