Literature DB >> 19109887

DNA Cytosine demethylation: are we getting close?

Josef Jiricny1, Mirco Menigatti.   

Abstract

Whether 5-methylcytosine (meC) can be enzymatically removed from vertebrate DNA has been the subject of extensive study and also some controversy. Rai et al. (2008) now report that cytosine demethylation can be accomplished in a one-cell zebrafish embryo by the combined action of a cytidine deaminase and a thymine DNA glycosylase.

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Year:  2008        PMID： 19109887     DOI： 10.1016/j.cell.2008.12.008

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  14 in total

1.  DNA methylation: superior or subordinate in the epigenetic hierarchy?

Authors:  Bilian Jin; Yajun Li; Keith D Robertson
Journal:  Genes Cancer       Date:  2011-06

Review 2.  Epigenetic choreography of stem cells: the DNA demethylation episode of development.

Authors:  Swayamsiddha Kar; Sabnam Parbin; Moonmoon Deb; Arunima Shilpi; Dipta Sengupta; Sandip Kumar Rath; Madhumita Rakshit; Aditi Patra; Samir Kumar Patra
Journal:  Cell Mol Life Sci       Date:  2013-10-10       Impact factor: 9.261

3.  Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation.

Authors:  Farah D Lubin
Journal:  Neurobiol Learn Mem       Date:  2011-03-16       Impact factor: 2.877

4.  GADD45A protein plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells.

Authors:  Rui-peng Zhang; Jian-zhong Shao; Li-xin Xiang
Journal:  J Biol Chem       Date:  2011-09-14       Impact factor: 5.157

Review 5.  Epigenetic reprogramming: is deamination key to active DNA demethylation?

Authors:  Marta Teperek-Tkacz; Vincent Pasque; George Gentsch; Anne C Ferguson-Smith
Journal:  Reproduction       Date:  2011-09-12       Impact factor: 3.906

6.  Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity.

Authors:  Phuong Pham; Peter Calabrese; Soo Jung Park; Myron F Goodman
Journal:  J Biol Chem       Date:  2011-05-12       Impact factor: 5.157

7.  TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model.

Authors:  Liang Ge; Rui-peng Zhang; Feng Wan; Dong-yang Guo; Ping Wang; Li-xin Xiang; Jian-zhong Shao
Journal:  Mol Cell Biol       Date:  2014-01-06       Impact factor: 4.272

Review 8.  DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker.

Authors:  Jörg Tost
Journal:  Mol Biotechnol       Date:  2010-01       Impact factor: 2.695

9.  Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Authors:  Mamta Tahiliani; Kian Peng Koh; Yinghua Shen; William A Pastor; Hozefa Bandukwala; Yevgeny Brudno; Suneet Agarwal; Lakshminarayan M Iyer; David R Liu; L Aravind; Anjana Rao
Journal:  Science       Date:  2009-04-16       Impact factor: 47.728

Review 10.  Active DNA demethylation mediated by DNA glycosylases.

Authors:  Jian-Kang Zhu
Journal:  Annu Rev Genet       Date:  2009       Impact factor: 16.830
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