Literature DB >> 19108695

A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT).

Uddhav Kumar Shigdel1, Chuan He.   

Abstract

A newly designed 1'-methylenedisulfide deoxyribose probe can efficiently cross-link to DNA cytosine-5-methyltransferases (DNMTs) through the active Cys residue, which provides a new tool to covalently trap DNMT-DNA complexes.

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Year:  2008        PMID: 19108695     DOI: 10.1021/ja8064304

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  3 in total

1.  Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.

Authors:  Chun-Xiao Song; Chuan He
Journal:  Acc Chem Res       Date:  2011-05-03       Impact factor: 22.384

2.  Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

Authors:  Christine Champion; Dominique Guianvarc'h; Catherine Sénamaud-Beaufort; Renata Z Jurkowska; Albert Jeltsch; Loïc Ponger; Paola B Arimondo; Anne-Laure Guieysse-Peugeot
Journal:  PLoS One       Date:  2010-08-24       Impact factor: 3.240

3.  Monitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensors.

Authors:  Toshikazu Ono; Sarah K Edwards; Shenliang Wang; Wei Jiang; Eric T Kool
Journal:  Nucleic Acids Res       Date:  2013-05-03       Impact factor: 16.971

  3 in total

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