Literature DB >> 19108170

Influence of metals on the activity of a bradykinin-destroying enzyme kininase.

P N Aarsen, A Kemp.   

Abstract

Kininase prepared from guinea-pig serum was inhibited by cysteine at pH 7.4 to 7.6. A similar effect was found with edetic acid. The enzyme blocked by edetic acid was reactivated immediately by addition of Mn(++), Co(++) and Zn(++). These findings indicate that kininase is a metal-activated enzyme.

Entities:  

Year:  1962        PMID： 19108170      PMCID： PMC1482212          DOI： 10.1111/j.1476-5381.1962.tb01448.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  5 in total

1.  An enzyme in human blood plasma that inactivates bradykinin and kallidins.

Authors:  E G ERDOS; E M SLOANE
Journal:  Biochem Pharmacol       Date:  1962-07       Impact factor: 5.858

2.  Naturally occurring lipidsoluble acids of pharmacological interest.

Authors:  W VOGT
Journal:  Pharmacol Rev       Date:  1958-09       Impact factor: 25.468

3.  Active polypeptides derived from plasma proteins.

Authors:  G P LEWIS
Journal:  Physiol Rev       Date:  1960-10       Impact factor: 37.312

4.  The estimation of urinary kallkrein.

Authors:  E W HORTON
Journal:  J Physiol       Date:  1959-10       Impact factor: 5.182

5.  Activation by glass of pharmacologically active agents in blood of various species.

Authors:  D ARMSTRONG; J B JEPSON; C A KEELE; J W STEWART
Journal:  J Physiol       Date:  1955-09-28       Impact factor: 5.182
  5 in total

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