Literature DB >> 19106198

Contemporary management of octogenarians hospitalized for heart failure in Europe: Euro Heart Failure Survey II.

Michel Komajda1, Olivier Hanon, Matthias Hochadel, Jose Luis Lopez-Sendon, Ferenc Follath, Piotr Ponikowski, Veli-Pekka Harjola, Helmut Drexler, Kenneth Dickstein, Luigi Tavazzi, Markku Nieminen.   

Abstract

AIMS: International guidelines are frequently not implemented in the elderly population with heart failure (HF). This study determined the management of octogenarians with HF enrolled in Euro Heart Failure Survey II (EHFS II) (2004-05). METHODS AND
RESULTS: We compared the clinical profile, 12 month outcomes, and management modalities between 741 octogenarians (median age 83.7 years) and 2836 younger patients (median age 68.4 years) hospitalized for acute/decompensated HF. Management modalities were also compared with those observed in EHFS I (2000-01). Female gender, new onset HF (de novo), hypertension, atrial fibrillation, co-morbidities, disabilities, and low quality of life were more common in the elderly (all P < 0.001). Mortality rates during hospital stay and during 12 months after discharge were increased in octogenarians (10.7 vs. 5.6% and 28.4 vs. 18.5%, P < 0.001). Underuse and underdosage of medications recommended for HF were observed in the elderly. However, a significant improvement was observed when compared with EHFS I both in the overall HF octogenarian population and in the subgroup with ejection fraction < or =45% for prescription rates of ACE-I/ARBs, beta-blockers, and aldosterone antagonists at discharge (82 vs. 71%; 56 vs. 29%; 54 vs. 18.5%, respectively, all P < 0.01), as well as for recommended combinations and dosage. Prescription rates remained stable for 12 months after discharge in survivors.
CONCLUSION: Our study confirms that the contemporary management of very elderly patients with HF remains suboptimal but that the situation is improving.

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Year:  2008        PMID: 19106198     DOI: 10.1093/eurheartj/ehn539

Source DB:  PubMed          Journal:  Eur Heart J        ISSN: 0195-668X            Impact factor:   29.983


  67 in total

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Review 9.  Heart failure in elderly patients: distinctive features and unresolved issues.

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Authors:  Alain Cohen-Solal; Dipak Kotecha; Dirk J van Veldhuisen; Daphne Babalis; Michael Böhm; Andrew J Coats; Michael Roughton; Philip Poole-Wilson; Luigi Tavazzi; Marcus Flather
Journal:  Eur J Heart Fail       Date:  2009-08-01       Impact factor: 15.534

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