Literature DB >> 19105747

First total synthesis of a polyunsaturated chromone metabolite isolated from the brown algae Zonaria tournefortii.

Hany F Anwar1, Trond Vidar Hansen.   

Abstract

Starting from the ethyl ester of eicosapentaenoic acid, the first total synthesis of the marine natural product all-(Z)-5,7-dihydroxy-2-(4Z,7Z,10Z,13Z,16Z-nonadecapentaenyl)chromone has been achieved in six steps and in 14% overall yield.

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Year:  2009        PMID： 19105747     DOI： 10.1021/ol802635a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator.

Authors:  M Aursnes; J E Tungen; A Vik; J Dalli; T V Hansen
Journal:  Org Biomol Chem       Date:  2013-11-19       Impact factor: 3.876

2.  Total synthesis of isokidamycin.

Authors:  B Michael O'Keefe; Douglas M Mans; David E Kaelin; Stephen F Martin
Journal:  J Am Chem Soc       Date:  2010-11-10       Impact factor: 15.419
  2 in total

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