Literature DB >> 19105216

De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes.

Hatsune Chiba1, Ryutaro Hirasawa, Masahiro Kaneda, Yuko Amakawa, En Li, Takashi Sado, Hiroyuki Sasaki.   

Abstract

Mouse blastocyst stage embryo stained for histone H3 lysine-27 trimethylation (red) and DNA (blue). H3K27me3 marks the inactive X chromosome. The study by Chiba et al. in this issue suggests that de novo DNA methyltransferases are dispensable for setting the imprint on the maternally-derived X chromsome in growing oocytes. See Chiba et al. in this issue.

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Year:  2008        PMID: 19105216     DOI: 10.1002/dvg.20496

Source DB:  PubMed          Journal:  Genesis        ISSN: 1526-954X            Impact factor:   2.487


  1 in total

Review 1.  Regulation of X-chromosome inactivation by the X-inactivation centre.

Authors:  Sandrine Augui; Elphège P Nora; Edith Heard
Journal:  Nat Rev Genet       Date:  2011-06       Impact factor: 53.242

  1 in total

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