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Literature DB >> 19104605

Design and demonstration of a small-animal up-conversion imager.

Christopher Salthouse¹, Scott Hildebrand, Ralph Weissleder, Umar Mahmood.

Abstract

This first small-animal up-conversion imager (SAUCI) was developed and used for in-vivo imaging of up-converting nanoparticles (UCNs.) Unlike traditional fluorophores, UCNs absorb multiple lower-energy photons and emit a single higher-energy photon. This unique physical process makes it possible to image deeper into tissue with lower background signals. In vivo imaging of particle accumulation in the liver was demonstrated following intravenous injection of particles.

Entities: Chemical Disease Species

Mesh：

Year: 2008 PMID： 19104605 PMCID： PMC2717740 DOI： 10.1364/oe.16.021731

Source DB: PubMed Journal: Opt Express ISSN： 1094-4087 Impact factor: 3.894

10 in total

Review 1. Shedding light onto live molecular targets.

Authors: Ralph Weissleder; Vasilis Ntziachristos
Journal: Nat Med Date: 2003-01 Impact factor: 53.440

Review 2. Infrared up-converting phosphors for bioassays.

Authors: P L A M Corstjens; S Li; M Zuiderwijk; K Kardos; W R Abrams; R S Niedbala; H J Tanke
Journal: IEE Proc Nanobiotechnol Date: 2005-04

3. Upconversion fluorescence enables homogeneous immunoassay in whole blood.

Authors: Katri Kuningas; Henna Päkkilä; Telle Ukonaho; Terhi Rantanen; Timo Lövgren; Tero Soukka
Journal: Clin Chem Date: 2007-01 Impact factor: 8.327

4. In vivo and scanning electron microscopy imaging of up-converting nanophosphors in Caenorhabditis elegans.

Authors: Shuang Fang Lim; Robert Riehn; William S Ryu; Nora Khanarian; Chih-Kuan Tung; David Tank; Robert H Austin
Journal: Nano Lett Date: 2006-02 Impact factor: 11.189

5. Versatile synthesis strategy for carboxylic acid-functionalized upconverting nanophosphors as biological labels.

Authors: Zhigang Chen; Huili Chen; He Hu; Mengxiao Yu; Fuyou Li; Qiang Zhang; Zhiguo Zhou; Tao Yi; Chunhui Huang
Journal: J Am Chem Soc Date: 2008-02-16 Impact factor: 15.419

6. Fluorescence-quenching-based enzyme-activity assay by using photon upconversion.

Authors: Terhi Rantanen; Marja-Leena Järvenpää; Johanna Vuojola; Katri Kuningas; Tero Soukka
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

7. A highly uniform UV transillumination imaging system for quantitative analysis of nucleic acids and proteins.

Authors: Bulbul Chakravarti; Melissa Louie; Wongrat Ratanaprayul; Alpan Raval; Sean Gallagher; Deb N Chakravarti
Journal: Proteomics Date: 2008-05 Impact factor: 3.984

Review 8. In vivo fluorescence imaging for tissue diagnostics.

Authors: S Andersson-Engels; C Klinteberg; K Svanberg; S Svanberg
Journal: Phys Med Biol Date: 1997-05 Impact factor: 3.609

9. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.

Authors: Andreas Wunder; Ching-Hsuan Tung; Ulf Müller-Ladner; Ralph Weissleder; Umar Mahmood
Journal: Arthritis Rheum Date: 2004-08

10. Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals.

Authors: Dev K Chatterjee; Abdul J Rufaihah; Yong Zhang
Journal: Biomaterials Date: 2007-12-03 Impact factor: 12.479

10 in total

6 in total

Review 6. Shedding light on nanomedicine.

Authors: Rong Tong; Daniel S Kohane
Journal: Wiley Interdiscip Rev Nanomed Nanobiotechnol Date: 2012-08-09