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Literature DB >> 1910138

Effects of amphetamine on T-cell immune response in mice.

M Freire-Garabal¹, J L Balboa, M J Núñez, M T Castaño, J B Llovo, J C Fernández-Rial, A Belmonte.

Abstract

Mice chronically injected with amphetamine (0.4 mg/kg/day) showed a reduction in thymus and spleen cellularity, and in peripheral T lymphocyte population. The blastogenic response of spleen lymphoid cells was assessed and amphetamine was found to inhibit T-cell proliferation. Amphetamine also reduced the capacity of mice to the development and passive transfer of immunity to Listeria monocytogenes.

Entities: Chemical Species

Mesh：

Substances：
Amphetamine

Year: 1991 PMID： 1910138 DOI： 10.1016/0024-3205(91)90570-2

Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037

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Cited

19 in total

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Effects of amphetamine on T-cell immune response in mice.

1. Recreational drug use and risk of Kaposi's sarcoma in HIV- and HHV-8-coinfected homosexual men.

Review 2. Neuropsychological consequences of HIV and substance abuse: a literature review and implications for treatment and future research.

3. Induction of apoptotic cell death in rat thymus and spleen after a bolus injection of methamphetamine.

4. Effects of amphetamine on development of oral candidiasis in rats.

Review 5. An Update of the Review of Neuropsychological Consequences of HIV and Substance Abuse: A Literature Review and Implications for Treatment and Future Research.

6. L-Deprenyl reverses age-associated decline in splenic norepinephrine, interleukin-2 and interferon-γ production in old female F344 rats.

Review 7. Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system.

8. Recreational amphetamine use and risk of HIV-related non-Hodgkin lymphoma.

9. Hematological, immunological and neurochemical effects of chronic amphetamine treatment in male rats.

10. Recreational drug use and T lymphocyte subpopulations in HIV-uninfected and HIV-infected men.