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Literature DB >> 19101208

No TRAP, no invasion.

Belinda J Morahan¹, Lina Wang, Ross L Coppel.

Abstract

Host-cell invasion by apicomplexan parasites is a unique process that is powered by the gliding motility motor and requires a transmembrane link between the parasite cytoskeleton and the host cell. The thrombospondin-related anonymous protein (TRAP) from Plasmodium plays such a part during sporozoite invasion by linking to actin through its cytoplasmic tail while binding to hepatocytes via its extracellular portion. In recent years, there have been major advances in the identification and characterization of TRAP-family proteins in the other invasive stages of Plasmodium as well as other Apicomplexa. This review summarizes the recent experimental data on these TRAP-family proteins, focusing on their structure and function.

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Year: 2008 PMID： 19101208 DOI： 10.1016/j.pt.2008.11.004

Source DB: PubMed Journal: Trends Parasitol ISSN： 1471-4922

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Cited

66 in total

1. Wet-surface-enhanced ellipsometric contrast microscopy identifies slime as a major adhesion factor during bacterial surface motility.

Authors: Adrien Ducret; Marie-Pierre Valignat; Fabrice Mouhamar; Tâm Mignot; Olivier Theodoly
Journal: Proc Natl Acad Sci U S A Date: 2012-06-04 Impact factor: 11.205

2. SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility.

Authors: Anke Harupa; Brandon K Sack; Viswanathan Lakshmanan; Nadia Arang; Alyse N Douglass; Brian G Oliver; Andrew B Stuart; D Noah Sather; Scott E Lindner; Kevin Hybiske; Motomi Torii; Stefan H I Kappe
Journal: Infect Immun Date: 2014-08-25 Impact factor: 3.441

3. Protein targeting to the parasitophorous vacuole membrane of Plasmodium falciparum.

Authors: Saliha Eksi; Kim C Williamson
Journal: Eukaryot Cell Date: 2011-04-15

4. Identification and Application of Epitopes in EtMIC1 of Eimeria tenella Recognized by the Monoclonal Antibodies 1-A1 and 1-H2.

Authors: Ningning Zhao; Shuzhen Ming; Yaru Lu; Fangkun Wang; Hongmei Li; Xiao Zhang; Xiaomin Zhao
Journal: Infect Immun Date: 2019-10-18 Impact factor: 3.441

No TRAP, no invasion.

1. Wet-surface-enhanced ellipsometric contrast microscopy identifies slime as a major adhesion factor during bacterial surface motility.

2. SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility.

3. Protein targeting to the parasitophorous vacuole membrane of Plasmodium falciparum.

4. Identification and Application of Epitopes in EtMIC1 of Eimeria tenella Recognized by the Monoclonal Antibodies 1-A1 and 1-H2.

5. Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP.

Review 6. Important Extracellular Interactions between Plasmodium Sporozoites and Host Cells Required for Infection.

7. Genomic Variation in IbA10G2 and Other Patient-Derived Cryptosporidium hominis Subtypes.

8. Structure of the micronemal protein 2 A/I domain from Toxoplasma gondii.

9. Biosynthesis of GDP-fucose and other sugar nucleotides in the blood stages of Plasmodium falciparum.

10. Geometric constrains for detecting short actin filaments by cryogenic electron tomography.