Literature DB >> 19100797

Pharmacokinetics and pharmacogenomics in breast cancer chemotherapy.

Sharon Marsh1, Geoffrey Liu.   

Abstract

Locally advanced or metastatic breast cancer is typically treated with chemotherapy. Multiple combinations of chemotherapy regimens are available, including anthracyclines, taxanes, antimetabolites, alkylating agents, platinum drugs and vinca alkaloids. This review discusses the pharmacokinetic and pharmacogenomic information available for commonly used breast cancer chemotherapy drugs. Pharmacogenomic associations for many drugs have yet to be identified or validated in breast cancer. Further work is needed to identify markers to screen breast cancer patients prior to therapy selection.

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Year:  2008        PMID： 19100797     DOI： 10.1016/j.addr.2008.10.003

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN： 0169-409X            Impact factor:   15.470


  6 in total

1.  Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer.

Authors:  Song Yao; William E Barlow; Kathy S Albain; Ji-Yeob Choi; Hua Zhao; Robert B Livingston; Warren Davis; James M Rae; I-Tien Yeh; Laura F Hutchins; Peter M Ravdin; Silvana Martino; Alan P Lyss; C Kent Osborne; Martin Abeloff; Gabriel N Hortobagyi; Daniel F Hayes; Christine B Ambrosone
Journal:  Clin Cancer Res       Date:  2010-12-15       Impact factor: 12.531

2.  A serum protein profile predictive of the resistance to neoadjuvant chemotherapy in advanced breast cancers.

Authors:  Seok-Won Hyung; Min Young Lee; Jong-Han Yu; Byunghee Shin; Hee-Jung Jung; Jong-Moon Park; Wonshik Han; Kyung-Min Lee; Hyeong-Gon Moon; Hui Zhang; Ruedi Aebersold; Daehee Hwang; Sang-Won Lee; Myeong-Hee Yu; Dong-Young Noh
Journal:  Mol Cell Proteomics       Date:  2011-07-28       Impact factor: 5.911

3.  Breast cancer in the personal genomics era.

Authors:  Rachel E Ellsworth; David J Decewicz; Craig D Shriver; Darrell L Ellsworth
Journal:  Curr Genomics       Date:  2010-05       Impact factor: 2.236

4.  Synthesis of 2- and 7-substituted C19 steroids having a 1,4,6-triene or 1,4-diene structure and their cytotoxic effects on T47D and MDA-MB231 breast cancer cells.

Authors:  Minwoo Kim; Eunsook Ma
Journal:  Molecules       Date:  2010-06-21       Impact factor: 4.411

5.  Serum Oxidative Stress Markers and Genotoxic Profile Induced by Chemotherapy in Patients with Breast Cancer: A Pilot Study.

Authors:  Antonio Luiz Gomes Júnior; Marcia Fernanda Correia Jardim Paz; Laís Iasmin Soares da Silva; Simone da Costa e Silva Carvalho; André Luiz Pinho Sobral; Kátia da Conceição Machado; Paulo Michel Pinheiro Ferreira; Prabodh Satyal; Rivelilson Mendes de Freitas; Ana Amélia de Carvalho Melo Cavalcante
Journal:  Oxid Med Cell Longev       Date:  2015-10-20       Impact factor: 6.543

6.  Analysis of the Doxorubicin and Doxorubicinol in the Plasma of Breast Cancer Patients for Monitoring the Toxicity of Doxorubicin.

Authors:  Yahdiana Harahap; Puspitasari Ardiningsih; Agatha Corintias Winarti; Denni Joko Purwanto
Journal:  Drug Des Devel Ther       Date:  2020-08-25       Impact factor: 4.162
  6 in total

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