Literature DB >> 19100698

Elite suppression of HIV-1 replication.

Joel N Blankson1, Robert F Siliciano.   

Abstract

Rare HIV-1-infected individuals are able to control viral replication without antiretroviral therapy. In this issue of Immunity, Migueles et al. (2008) show that HIV-1-specific CD8+ T cells from these individuals effectively suppress viral replication by granzyme B-mediated killing of target cells.

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Year:  2008        PMID: 19100698     DOI: 10.1016/j.immuni.2008.12.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  9 in total

Review 1.  Contribution of Sex Differences to HIV Immunology, Pathogenesis, and Cure Approaches.

Authors:  Jose A Moran; Shireen R Turner; Matthew D Marsden
Journal:  Front Immunol       Date:  2022-05-25       Impact factor: 8.786

2.  Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.

Authors:  Erin H Graf; Angela M Mexas; Jianqing J Yu; Farida Shaheen; Megan K Liszewski; Michele Di Mascio; Stephen A Migueles; Mark Connors; Una O'Doherty
Journal:  PLoS Pathog       Date:  2011-02-24       Impact factor: 6.823

Review 3.  Harnessing CD8+ T Cells Under HIV Antiretroviral Therapy.

Authors:  Joanna A Warren; Genevieve Clutton; Nilu Goonetilleke
Journal:  Front Immunol       Date:  2019-02-26       Impact factor: 7.561

4.  An integrative genomic analysis of transcriptional profiles identifies characteristic genes and patterns in HIV-infected long-term non-progressors and elite controllers.

Authors:  Jiwei Ding; Ling Ma; Jianyuan Zhao; Yongli Xie; Jinming Zhou; Xiaoyu Li; Shan Cen
Journal:  J Transl Med       Date:  2019-01-21       Impact factor: 5.531

5.  Transcriptional insights into the CD8+ T cell response in mono-HIV and HCV infection.

Authors:  Si-Yao Li; Zi-Ning Zhang; Yong-Jun Jiang; Ya-Jing Fu; Hong Shang
Journal:  J Transl Med       Date:  2020-02-24       Impact factor: 5.531

6.  Long-Term Non-Progression and Broad HIV-1-Specific Proliferative T-Cell Responses.

Authors:  Nesrina Imami; Samantha J Westrop; Nathali Grageda; Anna A Herasimtschuk
Journal:  Front Immunol       Date:  2013-03-01       Impact factor: 7.561

7.  Frequent Genetic Defects in the HIV-1 5' LTR/gag Gene in Hemophiliacs Treated with Korean Red Ginseng: Decreased Detection of Genetic Defects by Highly Active Antiretroviral Therapy.

Authors:  Young-Keol Cho; Yousun Jung; Heungsup Sung; Chul-Hyun Joo
Journal:  J Ginseng Res       Date:  2011-11       Impact factor: 6.060

8.  Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers.

Authors:  Samantha J Westrop; Nadeem A Qazi; Jeffrey Pido-Lopez; Mark R Nelson; Brian Gazzard; Frances M Gotch; Nesrina Imami
Journal:  PLoS One       Date:  2009-05-12       Impact factor: 3.240

9.  Analysis of ex vivo HIV-1 infection in a controller-discordant couple.

Authors:  Paradise Madlala; Paulien Van de Velde; Barbara Van Remoortel; Sofie Vets; Eric Van Wijngaerden; Kristel Van Laethem; Rik Gijsbers; Rik Schrijvers; Zeger Debyser
Journal:  J Virus Erad       Date:  2018-07-01
  9 in total

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