| Literature DB >> 19100696 |
Abstract
The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity, Chen et al. (2008) show that IRF-4-binding protein is a critical negative regulator of IRF-4 function, regulating production of the cytokines IL-21 and IL-17.Entities:
Mesh：
Substances：
Year: 2008 PMID： 19100696 DOI： 10.1016/j.immuni.2008.12.001
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745