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Literature DB >> 19100695

Alternative splicing of CD45: the tip of the iceberg.

Abstract

Mechanisms underlying the regulated splicing of CD45 RNA have been long-standing puzzles. In this issue of Immunity, Wu et al. (2008) identify hnRNPLL as a critical regulator of both signal-induced exon skipping in CD45 and global alternative-transcript expression in memory T cells.

Entities: Gene

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Year: 2008 PMID： 19100695 DOI： 10.1016/j.immuni.2008.12.005

Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745

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Cited

23 in total

1. Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.

Authors: C Pokoyski; T Lienen; S Rother; E Schock; A Plege-Fleck; R Geffers; R Schwinzer
Journal: Genes Immun Date: 2015-09-10 Impact factor: 2.676

Review 2. When one becomes many-Alternative splicing in β-cell function and failure.

Authors: Maria Inês Alvelos; Jonàs Juan-Mateu; Maikel Luis Colli; Jean-Valéry Turatsinze; Décio L Eizirik
Journal: Diabetes Obes Metab Date: 2018-09 Impact factor: 6.577

3. The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

Authors: Dominique Davidson; Ming-Chao Zhong; Pier Paolo Pandolfi; Silvia Bolland; Ramnik J Xavier; Brian Seed; Xin Li; Hua Gu; André Veillette
Journal: Cell Rep Date: 2016-12-06 Impact factor: 9.423

4. Identification of splice variants, targeted microRNAs and functional single nucleotide polymorphisms of the BOLA-DQA2 gene in dairy cattle.

Authors: Qinlei Hou; Jinming Huang; Zhihua Ju; Qiuling Li; Liming Li; Changfa Wang; Tao Sun; Lingling Wang; Minghai Hou; Suqin Hang; Jifeng Zhong
Journal: DNA Cell Biol Date: 2011-11-15 Impact factor: 3.311

Alternative splicing of CD45: the tip of the iceberg.

1. Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.

Review 2. When one becomes many-Alternative splicing in β-cell function and failure.

3. The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

4. Identification of splice variants, targeted microRNAs and functional single nucleotide polymorphisms of the BOLA-DQA2 gene in dairy cattle.

Review 5. Protein tyrosine phosphatases in lymphocyte activation and autoimmunity.

Review 6. A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes.

7. Splicing factor and exon profiling across human tissues.

8. RNAi screening: tips and techniques.

9. Estradiol regulates the expression of CD45 splicing isoforms in lymphocytes.

10. Investigating protein isoforms via proteomics: a feasibility study.