| Literature DB >> 19100409 |
T Chikaraishi1, H Sasaki, H Tsutsumi, S Miyano, R Nakazawa, T Nakano, K Kitajima, H Kudo, T Takahashi, Y Sato, K Kimura.
Abstract
We have designed a protocol for ABO-incompatible kidney transplantations based on preoperative plasmapheresis with a tacrolimus/mycophenolate mofetil/methylprednisolone/basiliximab protocol using low-dose rituximab (200 mg/body) instead of splenectomy to prevent antibody-mediated acute rejection. Eight patients successfully received transplants with this protocol. The titers of anti-A and -B antibodies as well as the number of CD20(+) cells were readily maintained at a low level posttransplantation. There were no side effects. All patients have renal transplant function with a follow-up of 1-34 months.Entities:
Mesh：
Substances：
Year: 2008 PMID： 19100409 DOI： 10.1016/j.transproceed.2008.06.110
Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066