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Literature DB >> 1909824

Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics.

F M Brodsky¹, B L Hill, S L Acton, I Näthke, D H Wong, S Ponnambalam, P Parham.

Abstract

Polymerization of clathrin triskelions into clathrin coats and subsequent disassembly by the heat shock protein hsc70 control receptor-mediated pathways of intracellular transport. The clathrin light chains are major regulatory elements in these processes. These polypeptides consist of linear arrays of functional domains with distinctive sequence motifs. Comparison of unicellular and multicellular eukaryotes reveals differences in the numbers of clathrin light chains and in the functional domains they contain.

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Year: 1991 PMID： 1909824 DOI： 10.1016/0968-0004(91)90087-c

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

28 in total

Review 1. Synaptic vesicle proteins and neuronal plasticity in adrenergic neurons.

Authors: X E Hou; A Dahlström
Journal: Neurochem Res Date: 2000-10 Impact factor: 3.996

2. Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans.

Authors: Chih-Ying Chen; Michael L Reese; Peter K Hwang; Nobuyuki Ota; David Agard; Frances M Brodsky
Journal: EMBO J Date: 2002-11-15 Impact factor: 11.598

3. Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast.

Authors: Thomas M Newpher; Sandra K Lemmon
Journal: Traffic Date: 2006-05 Impact factor: 6.215

4. Crystal structure at 2.8 A of the DLLRKN-containing coiled-coil domain of huntingtin-interacting protein 1 (HIP1) reveals a surface suitable for clathrin light chain binding.

Authors: Joel A Ybe; Sanjay Mishra; Stephen Helms; Jay Nix
Journal: J Mol Biol Date: 2006-12-23 Impact factor: 5.469

Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics.

Review 1. Synaptic vesicle proteins and neuronal plasticity in adrenergic neurons.

2. Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans.

3. Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast.

4. Crystal structure at 2.8 A of the DLLRKN-containing coiled-coil domain of huntingtin-interacting protein 1 (HIP1) reveals a surface suitable for clathrin light chain binding.

5. Human immunodeficiency virus type 1 and related primate lentiviruses engage clathrin through Gag-Pol or Gag.

6. The nucleation of receptor-mediated endocytosis.

7. A novel structural model for regulation of clathrin function.

8. Clathrin self-assembly is regulated by three light-chain residues controlling the formation of critical salt bridges.

9. Clathrin light chains regulate clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis.

10. Clathrin light chain B: gene structure and neuron-specific splicing.