Literature DB >> 19097823

Conservative treatment of phimosis with fluticasone proprionate 0.05%: a clinical study in 1185 boys.

Nick Zavras1, Efstratios Christianakis, Demetrios Mpourikas, Khalil Ereikat.   

Abstract

OBJECTIVE: Circumcision has been the traditional method of choice in the treatment of boys with phimosis. Recently, several published studies worldwide have focused their interest on more conservative approaches in management of this condition. These studies advocate the use of topical steroids in the phimotic foreskin. We aimed to investigate the efficacy and safety of a medium potency corticosteroid in boys with different types of prepuce retractabilty. PATIENTS AND METHODS: A prospective study was performed involving boys referred to our hospital for possible phimosis between January 2004 and February 2008. All were treated initially with fluticasone proprionate 0.05% for a period of 4-8 weeks. Patients were reassessed after 6 months of follow up.
RESULTS: A total of 1185 boys with a diagnosis of phimosis were treated with fluticasone proprionate 0.05%. Successful results were achieved in 1079 (91.1%) patients including boys with mild balanitis xerotica obliterans. No side effects were noticed.
CONCLUSION: Our results show that fluticasone proprionate 0.05%, a mild potent corticosteroid, is effective and safe in the treatment of boys with different types of phimosis.

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Year:  2008        PMID: 19097823     DOI: 10.1016/j.jpurol.2008.11.006

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  6 in total

1.  [Nonretractable foreskin in boys without complaints : An indication for circumcision?]

Authors:  K Eckert; N Janssen; M Franz; P Liedgens
Journal:  Urologe A       Date:  2017-03       Impact factor: 0.639

Review 2.  [Current and practice-relevant news from pediatric urology].

Authors:  R Stein; A Schröder; M Goepel
Journal:  Urologe A       Date:  2011-09       Impact factor: 0.639

3.  Canadian Urological Association guideline on the care of the normal foreskin and neonatal circumcision in Canadian infants (full version).

Authors:  Sumit Dave; Kourosh Afshar; Luis H Braga; Peter Anderson
Journal:  Can Urol Assoc J       Date:  2017-12-01       Impact factor: 1.862

Review 4.  Is steroids therapy effective in treating phimosis? A meta-analysis.

Authors:  Jiaming Liu; Jin Yang; Yuntian Chen; Sihang Cheng; Chao Xia; Tuo Deng
Journal:  Int Urol Nephrol       Date:  2016-01-02       Impact factor: 2.370

5.  Effect of topical steroid (0.05% clobetasol propionate) treatment in children with severe phimosis.

Authors:  Chan Ho Lee; Sang Don Lee
Journal:  Korean J Urol       Date:  2013-09-10

6.  Efficacy of topical steroid treatment in children with severe phimosis in China: A long-term single centre prospective study.

Authors:  Guanglun Zhou; Man Jiang; Zhilin Yang; Wanhua Xu; Shoulin Li
Journal:  J Paediatr Child Health       Date:  2021-07-02       Impact factor: 1.929

  6 in total

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