| Literature DB >> 19096802 |
Niloufar Safinia1, Stephen L Minger.
Abstract
Use of human hepatocytes for therapeutic and drug discovery applications is hampered by limited tissue source and the inability of hepatocytes to proliferate and maintain function long-term in vitro. Human embryonic stem (hES) cells are immortal and pluripotent and may provide a cell source for functional human hepatocytes (1) Here we have outlined some of the protocols currently in use for the generation of hepatocytes from hES cells.Entities:
Mesh:
Year: 2009 PMID: 19096802 DOI: 10.1007/978-1-59745-201-4_14
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745