Literature DB >> 19096797

Isolation of human hepatocytes.

Ragai R Mitry1.   

Abstract

Protocols for isolation of human hepatocytes have been developed. The isolated cells can be used not only in research but also for transplantation in patients with liver disease, especially acute liver failure and liver-based metabolic/synthetic conditions. The aim of hepatocyte transplantation is to correct the missing liver function(s) and allow either the recovery of the liver or buy the patient time until a suitable donor liver is available for transplantation.

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Year:  2009        PMID： 19096797     DOI： 10.1007/978-1-59745-201-4_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  11 in total

1.  Human umbilical cord matrix stem cells efficiently rescue acute liver failure through paracrine effects rather than hepatic differentiation.

Authors:  Shichang Zhang; Li Chen; Tao Liu; Bo Zhang; Dedong Xiang; Zhengguo Wang; Yingjie Wang
Journal:  Tissue Eng Part A       Date:  2012-06-05       Impact factor: 3.845

2.  Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization.

Authors:  Andrea Vettori; David Greenald; Garrick K Wilson; Margherita Peron; Nicola Facchinello; Eleanor Markham; Mathavan Sinnakaruppan; Laura C Matthews; Jane A McKeating; Francesco Argenton; Fredericus J M van Eeden
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-29       Impact factor: 11.205

3.  Integration of single-layer skin hollow fibers and scaffolds develops a three-dimensional hybrid bioreactor for bioartificial livers.

Authors:  Shichang Zhang; Li Chen; Tao Liu; Zhengguo Wang; Yingjie Wang
Journal:  J Mater Sci Mater Med       Date:  2013-08-21       Impact factor: 3.896

4.  A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration.

Authors:  Garrick K Wilson; Claire L Brimacombe; Ian A Rowe; Gary M Reynolds; Nicola F Fletcher; Zania Stamataki; Ricky H Bhogal; Maria L Simões; Margaret Ashcroft; Simon C Afford; Ragai R Mitry; Anil Dhawan; Christopher J Mee; Stefan G Hübscher; Peter Balfe; Jane A McKeating
Journal:  J Hepatol       Date:  2011-12-16       Impact factor: 25.083

5.  Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.

Authors:  Suttiruk Jitraruch; Anil Dhawan; Robin D Hughes; Celine Filippi; Daniel Soong; Christina Philippeos; Sharon C Lehec; Nigel D Heaton; Maria S Longhi; Ragai R Mitry
Journal:  PLoS One       Date:  2014-12-01       Impact factor: 3.240

Review 6.  Hepatitis C virus infection of cholangiocarcinoma cell lines.

Authors:  Nicola F Fletcher; Elizabeth Humphreys; Elliott Jennings; William Osburn; Samantha Lissauer; Garrick K Wilson; Sven C D van IJzendoorn; Thomas F Baumert; Peter Balfe; Simon Afford; Jane A McKeating
Journal:  J Gen Virol       Date:  2015-02-20       Impact factor: 3.891

7.  Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes.

Authors:  Harry H Qin; Céline Filippi; Song Sun; Sharon Lehec; Anil Dhawan; Robin D Hughes
Journal:  Stem Cell Res Ther       Date:  2015-12-01       Impact factor: 6.832

8.  Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection.

Authors:  Garrick K Wilson; Michelle J Farquhar; Luke Meredith; Anil Dhawan; Ragai Mitry; Peter Balfe; Jane A McKeating
Journal:  J Gen Virol       Date:  2015-02-09       Impact factor: 3.891

9.  Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host.

Authors:  Richard J P Brown; Natalia Hudson; Garrick Wilson; Shafiq Ur Rehman; Sara Jabbari; Ke Hu; Alexander W Tarr; Persephone Borrow; Michael Joyce; Jamie Lewis; Lin Fu Zhu; Mansun Law; Norman Kneteman; D Lorne Tyrrell; Jane A McKeating; Jonathan K Ball
Journal:  J Virol       Date:  2012-08-01       Impact factor: 5.103

10.  Cryopreservation of Hepatocyte Microbeads for Clinical Transplantation.

Authors:  Suttiruk Jitraruch; Anil Dhawan; Robin D Hughes; Celine Filippi; Sharon C Lehec; Leanne Glover; Ragai R Mitry
Journal:  Cell Transplant       Date:  2017-08       Impact factor: 4.064
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