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Literature DB >> 19095325

Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic Zucker rats.

Niloofar M Tabatabai¹, Mukut Sharma, Samuel S Blumenthal, David H Petering.

Abstract

Diabetes-mediated changes in mRNA expressions of kidney glucose transporters SGLT1 and SGLT2 were investigated in Zucker rats. SGLTs expressions in pre-diabetic obese rats were similar to leans. SGLT1 and SGLT2 levels in diabetic obese rats were 1.6 (P<0.03) and 4.8 (P<0.002) folds higher than age-matched leans, respectively.

Entities: Chemical Disease Gene Species

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Year: 2008 PMID： 19095325 PMCID： PMC2652566 DOI： 10.1016/j.diabres.2008.11.003

Source DB: PubMed Journal: Diabetes Res Clin Pract ISSN： 0168-8227 Impact factor: 5.602

17 in total

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