| Literature DB >> 1909414 |
J Tateishi1, T Tashima, T Kitamoto.
Abstract
Chemical inactivation of pathogen of Creutzfeldt-Jakob disease (CJD) was examined using the mouse-adapted CJD strain. A high concentration of formic acid, guanidine compounds, trichloroacetate and phenol prevented CJD transmission. NaOH between 0.25 and 2 N lengthened the incubation periods. Sodium dodecyl sulfate (SDS) in a concentration between 1 and 3% did not alter incubation at room temperature but did completely block the transmission after boiling for 3 min in 3% SDS. This method is recommended for practical disinfection.Entities:
Mesh:
Substances:
Year: 1991 PMID: 1909414 DOI: 10.1111/j.1348-0421.1991.tb01544.x
Source DB: PubMed Journal: Microbiol Immunol ISSN: 0385-5600 Impact factor: 1.955