Literature DB >> 19094136

Ecthyma gangrenosum: an important feature of pseudomonal sepsis in a previously well child.

S I Goolamali1, A Fogo, L Killian, H Shaikh, N Brathwaite, M Ford-Adams, S Macfarlane.   

Abstract

Ecthyma gangrenosum is a rare, distinctive skin disorder associated with potentially fatal underlying pseudomonal sepsis. Although typically occurring in neutropenic or immunocompromised patients, it can occasionally affect healthy children. The appearances are characteristic with small indurated vesicular papules progressing rapidly to infarcted necrotic areas with surrounding erythema and a typical black eschar. In young children, these are often accompanied by fever and diarrhoea. The absence of suppuration and slough distinguishes it from the more recognized pyoderma gangrenosum. Lesions can occur at any site although are most commonly found over the buttocks, limbs, axillae and perineum. We describe the case of a 28-month-old, previously well child who presented with typical features of ecthyma gangrenosum secondary to Pseudomonas infection who responded to appropriate antibiotic treatment. Despite a thorough search, no underlying cause was found. Early recognition and prompt treatment with antipseudomonal antibiotics is vital to reduce morbidity and potential mortality.

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Year:  2009        PMID: 19094136     DOI: 10.1111/j.1365-2230.2008.03020.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  6 in total

1.  A case of perineal ecthyma gangrenosum.

Authors:  Zeynep Meltem Akkurt; Veysi Fidan; Derya Uçmak; Tuba Dal; Selvi Kelekçi; Haydar Uçak
Journal:  Turk Pediatri Ars       Date:  2016-03-01

2.  Impact of Type III Secretion Effectors and of Phenoxyacetamide Inhibitors of Type III Secretion on Abscess Formation in a Mouse Model of Pseudomonas aeruginosa Infection.

Authors:  Bryan J Berube; Katherine R Murphy; Matthew C Torhan; Nicholas O Bowlin; John D Williams; Terry L Bowlin; Donald T Moir; Alan R Hauser
Journal:  Antimicrob Agents Chemother       Date:  2017-10-24       Impact factor: 5.191

3.  Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report.

Authors:  Stephanie Biscaye; Diane Demonchy; Mickael Afanetti; Audrey Dupont; Herve Haas; Antoine Tran
Journal:  Medicine (Baltimore)       Date:  2017-01       Impact factor: 1.889

4.  Ecthyma gangrenosum in a 3-month-old, previously healthy infant: A Case Report.

Authors:  Xiao-Ting Zhang; Wan-Wan Jin; Xin-Hua Ma; Hai-Feng Yu; Xu-Hua Tang
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

5.  Ecthyma gangrenosum and severe neutropenic sepsis caused by Staphylococcus aureus infection in a previously healthy child: a case report.

Authors:  Xinjuan Zhang; Yanping Yu
Journal:  J Int Med Res       Date:  2022-09       Impact factor: 1.573

6.  Ecthyma gangrenosum in a previously healthy patient.

Authors:  Ilkay Bozkurt; Esra Pancar Yuksel; Mustafa Sunbul
Journal:  Indian Dermatol Online J       Date:  2015 Sep-Oct
  6 in total

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