Literature DB >> 19093803

Stable preformed chiral palladium catalysts for the one-pot asymmetric reductive amination of ketones.

Laura Rubio-Pérez1, F Javier Pérez-Flores, Pankaj Sharma, Luis Velasco, Armando Cabrera.   

Abstract

The application of air stable preformed [(R)-BINAP]PdBr2, [(S)-BINAP]PdBr2, [(R)-Tol-BINAP]PdBr2, and [(S,S)-CHIRAPHOS]PdBr2 complexes in the one-pot asymmetric reductive amination of various carbonyl compounds, leading to chiral amines in very good yields with high enantioselectivities (<99% ee), is reported.

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Year:  2009        PMID: 19093803     DOI: 10.1021/ol802336m

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  A Modified System for the Synthesis of Enantioenriched N-Arylamines through Copper-Catalyzed Hydroamination.

Authors:  Saki Ichikawa; Shaolin Zhu; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2018-06-12       Impact factor: 15.336

2.  Iridium-catalyzed direct asymmetric reductive amination utilizing primary alkyl amines as the N-sources.

Authors:  Zitong Wu; Wenji Wang; Haodong Guo; Guorui Gao; Haizhou Huang; Mingxin Chang
Journal:  Nat Commun       Date:  2022-06-10       Impact factor: 17.694

3.  Bifunctional catalysis: direct reductive amination of aliphatic ketones with an iridium-phosphate catalyst.

Authors:  Barbara Villa-Marcos; Chaoqun Li; Keith R Mulholland; Philip J Hogan; Jianliang Xiao
Journal:  Molecules       Date:  2010-04-08       Impact factor: 4.411

4.  One-Pot Synthesis of Chiral N-Arylamines by Combining Biocatalytic Aminations with Buchwald-Hartwig N-Arylation.

Authors:  Sebastian C Cosgrove; Matthew P Thompson; Syed T Ahmed; Fabio Parmeggiani; Nicholas J Turner
Journal:  Angew Chem Int Ed Engl       Date:  2020-08-11       Impact factor: 15.336

  4 in total

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