Literature DB >> 19090973

What is a virulence factor?

Alan S Cross1.   

Abstract

Bacterial virulence factors enable a host to replicate and disseminate within a host in part by subverting or eluding host defenses. The use of genomic techniques has led to the identification of new virulence factors that may serve as targets for new therapies. These putative virulence factors must be rigorously evaluated with in vitro and in vivo studies with an awareness of the technical limitations of each approach as well as an assessment of the prevalence of this factor in clinical bacterial isolates retrieved from appropriately controlled epidemiologic studies.

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Year:  2008        PMID： 19090973      PMCID： PMC2646308          DOI： 10.1186/cc7127

Source DB:  PubMed          Journal:  Crit Care        ISSN： 1364-8535            Impact factor:   9.097


  8 in total

1.  Immunochemical similarity between polysaccharide antigens of Escherichia coli 07: K1(L):NM and group B Neisseria meningitidis.

Authors:  D L Kasper; J L Winkelhake; W D Zollinger; B L Brandt; M S Artenstein
Journal:  J Immunol       Date:  1973-01       Impact factor: 5.422

Review 2.  Choice of bacteria in animal models of sepsis.

Authors:  A S Cross; S M Opal; J C Sadoff; P Gemski
Journal:  Infect Immun       Date:  1993-07       Impact factor: 3.441

3.  The importance of the K1 capsule in invasive infections caused by Escherichia coli.

Authors:  A S Cross; P Gemski; J C Sadoff; F Orskov; I Orskov
Journal:  J Infect Dis       Date:  1984-02       Impact factor: 5.226

4.  Plasma endotoxin concentration in healthy primates and during E. coli-induced shock.

Authors:  B C Wessels; M T Wells; S L Gaffin; J G Brock-Utne; P Gathiram; L B Hinshaw
Journal:  Crit Care Med       Date:  1988-06       Impact factor: 7.598

5.  Molecular cloning of the K1 capsular polysaccharide genes of E. coli.

Authors:  R P Silver; C W Finn; W F Vann; W Aaronson; R Schneerson; P J Kretschmer; C F Garon
Journal:  Nature       Date:  1981-02-19       Impact factor: 49.962

6.  Mouse virulence of K(L) antigen-containing strains of Escherichia coli.

Authors:  G Wolberg; C W DeWitt
Journal:  J Bacteriol       Date:  1969-11       Impact factor: 3.490

7.  The importance of a lipopolysaccharide-initiated, cytokine-mediated host defense mechanism in mice against extraintestinally invasive Escherichia coli.

Authors:  A Cross; L Asher; M Seguin; L Yuan; N Kelly; C Hammack; J Sadoff; P Gemski
Journal:  J Clin Invest       Date:  1995-08       Impact factor: 14.808

Review 8.  Bench-to-bedside review: Bacterial virulence and subversion of host defences.

Authors:  Steven A R Webb; Charlene M Kahler
Journal:  Crit Care       Date:  2008-11-10       Impact factor: 9.097
  8 in total
  10 in total

1.  Stress Response Protein BolA Influences Fitness and Promotes Salmonella enterica Serovar Typhimurium Virulence.

Authors:  Dalila Mil-Homens; Susana Barahona; Ricardo N Moreira; Inês J Silva; Sandra N Pinto; Arsénio M Fialho; Cecília M Arraiano
Journal:  Appl Environ Microbiol       Date:  2018-04-02       Impact factor: 4.792

Review 2.  Intruders below the radar: molecular pathogenesis of Bartonella spp.

Authors:  Alexander Harms; Christoph Dehio
Journal:  Clin Microbiol Rev       Date:  2012-01       Impact factor: 26.132

3.  Genomic Investigation into the Virulome, Pathogenicity, Stress Response Factors, Clonal Lineages, and Phylogenetic Relationship of Escherichia coli Strains Isolated from Meat Sources in Ghana.

Authors:  Frederick Adzitey; Jonathan Asante; Hezekiel M Kumalo; Rene B Khan; Anou M Somboro; Daniel G Amoako
Journal:  Genes (Basel)       Date:  2020-12-14       Impact factor: 4.096

Review 4.  Incompatibility Group I1 (IncI1) Plasmids: Their Genetics, Biology, and Public Health Relevance.

Authors:  Steven L Foley; Pravin R Kaldhone; Steven C Ricke; Jing Han
Journal:  Microbiol Mol Biol Rev       Date:  2021-04-28       Impact factor: 11.056

5.  Prediction of virulence factors using bioinformatics approaches.

Authors:  Rupanjali Chaudhuri; Srinivasan Ramachandran
Journal:  Methods Mol Biol       Date:  2014

Review 6.  Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current Challenges, and Future Prospects for Cancer Immunotherapy.

Authors:  Kajal H Gupta; Christina Nowicki; Eileena F Giurini; Amanda L Marzo; Andrew Zloza
Journal:  Vaccines (Basel)       Date:  2021-12-18

7.  Vaginal microbiota differences associated with pelvic organ prolapse risk during late gestation in commercial sows†.

Authors:  Zoë E Kiefer; Lucas R Koester; Jamie M Studer; Amanda L Chipman; Christine Mainquist-Whigham; Aileen F Keating; Stephan Schmitz-Esser; Jason W Ross
Journal:  Biol Reprod       Date:  2021-12-20       Impact factor: 4.285

8.  Structure, Biosynthesis, and Biological Activity of Succinylated Forms of Bacteriocin BacSp222.

Authors:  Justyna Śmiałek; Michał Nowakowski; Monika Bzowska; Oliwia Bocheńska; Agnieszka Wlizło; Andrzej Kozik; Grzegorz Dubin; Paweł Mak
Journal:  Int J Mol Sci       Date:  2021-06-10       Impact factor: 5.923

9.  Aetiology of bacteraemia as a risk factor for septic shock at the onset of febrile neutropaenia in adult cancer patients.

Authors:  Regis Goulart Rosa; Luciano Zubaran Goldani
Journal:  Biomed Res Int       Date:  2014-03-20       Impact factor: 3.411

Review 10.  Polyphosphate Kinase 2 (PPK2) Enzymes: Structure, Function, and Roles in Bacterial Physiology and Virulence.

Authors:  Nolan Neville; Nathan Roberge; Zongchao Jia
Journal:  Int J Mol Sci       Date:  2022-01-08       Impact factor: 5.923
  10 in total

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