Frequency of different types of ovarian cancer in Vali-e-Asr Hospital (Tehran University of Medical Sciences) 2001-2003.

Purpose of this study was to report histology specific age adjusted ovarian cancer incidence rates from 2001-2003 in Tehran University Hospital (valie-Asr hospital). This was a case series study including all microscopically confirmed cases of ovarian malignancies from 2001-2003. There were 152 cases of ovarian cancer, 102 (67.1%) epithelial type, 26 (17.1%) germ cell tumors, 14 (9.2%) sex cord stromal and 10 (6.6%) metastatic ovarian tumors. Present results were compatible with results from nonwestern countries. Epithelial type tumors and sex cord-stromal tumors were more prevalent after the age 50 (40 and 44.4% consequently). Germ cell tumors were more prevalent before 20(16 cases, 61.5%) (chi2 = 42.54, p-value = 0.000). Stage of disease in epithelial type tumors was advanced in most of patients but most germ cell tumors and sexcord-stromal tumors were stage I (chi2 = 19.6, p-value = 0.000). Present study showed that epithelial ovarian tumors in comparison to western countries are less frequent in Iran but still this histologic type is the most prevalent type of ovarian malignancy in this area of the world. Of course in younger patients we can predict more probability of germ cell tumors with more localized disease and better prognosis.