Literature DB >> 19089829

Polyprenylated xanthones from Garcinia lancilimba showing apoptotic effects against HeLa-C3 cells.

Quan-Bing Han1, Hong-Lei Tian, Nian-Yun Yang, Chun-Feng Qiao, Jing-Zheng Song, Donald C Chang, Kathy Q Luo, Hong-Xi Xu.   

Abstract

Three new prenylated xanthones, 1-3, along with ten known compounds, were isolated from the stem bark of Garcinia lancilimba. Their structures were elucidated by extensive spectroscopic analysis, including 1D- and 2D-NMR spectra, as well as HR-MS experiments. Some of these compounds showed apoptotic effects or growth-inhibition effects against HeLa cells expressing a caspase sensor protein.

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Year:  2008        PMID： 19089829     DOI： 10.1002/cbdv.200890225

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  6 in total

1.  Three new xanthones from the leaves of Garcinia lancilimba.

Authors:  Yating Sun; Dahong Li; Cuicui Jia; Chunmei Xue; Jiao Bai; Zhanlin Li; Huiming Hua
Journal:  J Nat Med       Date:  2015-12-08       Impact factor: 2.343

2.  Proteasome-inhibitory and cytotoxic constituents of Garcinia lateriflora: absolute configuration of caged xanthones.

Authors:  Yulin Ren; Daniel D Lantvit; Esperanza J Carcache de Blanco; Leonardus B S Kardono; Soedarsono Riswan; Heebyung Chai; Charles E Cottrell; Norman R Farnsworth; Steven M Swanson; Yuanqing Ding; Xing-Cong Li; Jannie P J Marais; Daneel Ferreira; A Douglas Kinghorn
Journal:  Tetrahedron       Date:  2010-07-17       Impact factor: 2.457

3.  Oblongifolin C inhibits metastasis by up-regulating keratin 18 and tubulins.

Authors:  Xiaoyu Wang; Yuanzhi Lao; Naihan Xu; Zhichao Xi; Man Wu; Hua Wang; Xiyi Li; Hongsheng Tan; Menghong Sun; Hongxi Xu
Journal:  Sci Rep       Date:  2015-05-14       Impact factor: 4.379

4.  The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation.

Authors:  Xin Li; Yuanzhi Lao; Hong Zhang; Xiaoyu Wang; Hongsheng Tan; Zhixiu Lin; Hongxi Xu
Journal:  BMC Cancer       Date:  2015-04-11       Impact factor: 4.430

5.  Brevipedicelones D and E, Two C-O-C Flavonoid Dimmers from the Leaves of Garcinia brevipedicellata and Anti-onchocercal Activity.

Authors:  Mirabel Akongwi; Anastasie E Tih; Kennedy D Nyongbela; Moses Samje; Raphael T Ghogomu; Bernard Bodo
Journal:  Nat Prod Bioprospect       Date:  2018-12-03

6.  The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation.

Authors:  Yuanzhi Lao; Gang Wan; Zhenyan Liu; Xiaoyu Wang; Ping Ruan; Wei Xu; Danqing Xu; Weidong Xie; Yaou Zhang; Hongxi Xu; Naihan Xu
Journal:  Autophagy       Date:  2014-02-14       Impact factor: 16.016
  6 in total

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