Literature DB >> 19089693

Atherosclerotic plaque development and instability: a dual role for VEGF.

Pieter W Holm1, Riemer H J A Slart, Clark J Zeebregts, Jan L Hillebrands, René A Tio.   

Abstract

Vascular endothelial growth factor (VEGF), a potent growth factor for endothelial cells and inducer of angiogenesis, is important for endothelial integrity and thus for vascular function. On the other hand, VEGF may enhance the pathophysiologic mechanism of plaque formation and plaque destabilization. In this review we discuss the data available so far for VEGF as angiogenic and/or inflammatory cytokine in the vulnerable atherosclerotic plaque.

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Year:  2009        PMID： 19089693     DOI： 10.1080/07853890802516507

Source DB:  PubMed          Journal:  Ann Med        ISSN： 0785-3890            Impact factor:   4.709


  30 in total

1.  Gender-dependent correlations of carotid intima-media thickness with gene expression in blood.

Authors:  Renée J Turner; Cheryl D Bushnell; Thomas C Register; Frank R Sharp
Journal:  Transl Stroke Res       Date:  2011-06       Impact factor: 6.829

2.  VEGF pathway inhibition by anticancer agent sunitinib and susceptibility to atherosclerosis plaque disruption.

Authors:  Stanislas Ropert; Olivier Vignaux; Olivier Mir; François Goldwasser
Journal:  Invest New Drugs       Date:  2010-07-30       Impact factor: 3.850

3.  Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2.

Authors:  Unni M Chandrasekharan; Matthew Waitkus; Corttrell M Kinney; Alicia Walters-Stewart; Paul E DiCorleto
Journal:  Arterioscler Thromb Vasc Biol       Date:  2010-07-29       Impact factor: 8.311

4.  Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE-/- Mice.

Authors:  Yared Tekabe; Lynne L Johnson; Krissy Rodriquez; Qing Li; Marina Backer; Joseph M Backer
Journal:  Mol Imaging Biol       Date:  2018-02       Impact factor: 3.488

5.  Circulating angiogenic cell function is inhibited by cortisol in vitro and associated with psychological stress and cortisol in vivo.

Authors:  Kirstin Aschbacher; Ronak Derakhshandeh; Abdiel J Flores; Shilpa Narayan; Wendy Berry Mendes; Matthew L Springer
Journal:  Psychoneuroendocrinology       Date:  2016-02-23       Impact factor: 4.905

6.  Single-chain VEGF/Cy5.5 targeting vegf receptors to indicate atherosclerotic plaque instability.

Authors:  Ming Kai Lam; Sali Al-Ansari; Gooitzen M van Dam; René A Tio; Jan-Cees Breek; Riemer H J A Slart; Jan-Luuk Hillebrands; Clark J Zeebregts
Journal:  Mol Imaging Biol       Date:  2013-06       Impact factor: 3.488

7.  Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis.

Authors:  Rong Liu; J-P Jin
Journal:  J Mol Cell Cardiol       Date:  2016-08-26       Impact factor: 5.000

Review 8.  Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells.

Authors:  Giovanni Anfossi; Isabella Russo; Gabriella Doronzo; Alice Pomero; Mariella Trovati
Journal:  Mediators Inflamm       Date:  2010-06-28       Impact factor: 4.711

Review 9.  Tyrosine Kinase Inhibitors and Vascular Toxicity: Impetus for a Classification System?

Authors:  Joerg Herrmann
Journal:  Curr Oncol Rep       Date:  2016-06       Impact factor: 5.075

Review 10.  Protein kinase Calpha: disease regulator and therapeutic target.

Authors:  Olga Konopatskaya; Alastair W Poole
Journal:  Trends Pharmacol Sci       Date:  2009-12-05       Impact factor: 14.819
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