Literature DB >> 19089626

Use of Coaxil (tianeptine) in elderly patients with combined mild cognitive and depressive-anxiety disorders.

I B Karpukhin1.   

Abstract

The studies reported here addressed 20 patients aged 60-69 years whose clinical picture combined the manifestations of mild dementia with those of mild depression and anxiety. Patients were treated with Coaxil (tianeptine) for 60 days at a dose of 37.5 mg/day. Patients were assessed by clinical-psychological investigations with addition of the Hamilton scales and neuropsychological testing by the Luriya method. Coaxil was found to be highly effective in relation to all psychopathological components. Recommendations for the use of Coaxil in elderly patients with cognitive and depressive-anxiety disorders are formulated.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19089626     DOI： 10.1007/s11055-008-9099-x

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN： 0097-0549


  7 in total

1.  Age dependent effects of 5-hydroxytryptamine upon memory consolidation and cerebral protein synthesis.

Authors:  W B Essman
Journal:  Pharmacol Biochem Behav       Date:  1973 Jan-Feb       Impact factor: 3.533

2.  Action of tianeptine on focalization of attention in cat.

Authors:  P Delagrange; J J Bouyer; M F Montaron; C Durand; E Mocaër; A Rougeul
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

3.  [Mild dementia syndrome in middle and old age].

Authors:  G A Zharikov
Journal:  Zh Nevrol Psikhiatr Im S S Korsakova       Date:  1998

4.  Efficacy of tianeptine in anxious-depressed patients: results of a controlled multicenter trial versus amitriptyline.

Authors:  J D Guelfi; P Pichot; J F Dreyfus
Journal:  Neuropsychobiology       Date:  1989       Impact factor: 2.328

5.  Clinical safety and efficacy of tianeptine in 1,858 depressed patients treated in general practice.

Authors:  J D Guelfi; C Dulcire; P Le Moine; A Tafani
Journal:  Neuropsychobiology       Date:  1992       Impact factor: 2.328

6.  [Epidemiology of dementias in the middle-aged and elderly].

Authors:  S I Gavrilova; L O Sudareva; Ia B Kalyn
Journal:  Zh Nevropatol Psikhiatr Im S S Korsakova       Date:  1987

7.  [Major depressive episodes in patients over 70 years of age. Evaluation of the efficiency and acceptability of tianeptine and mianserin].

Authors:  S Brion; S Audrain; C de Bodinat
Journal:  Presse Med       Date:  1996-03-16       Impact factor: 1.228
  7 in total
  3 in total

1.  The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor.

Authors:  Benjamin Adam Samuels; Katherine M Nautiyal; Andrew C Kruegel; Marjorie R Levinstein; Valerie M Magalong; Madalee M Gassaway; Steven G Grinnell; Jaena Han; Michael A Ansonoff; John E Pintar; Jonathan A Javitch; Dalibor Sames; René Hen
Journal:  Neuropsychopharmacology       Date:  2017-03-17       Impact factor: 7.853

2.  Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine.

Authors:  Jaena Han; Valentine Andreu; Cory Langreck; Elizabeth A Pekarskaya; Steven G Grinnell; Florence Allain; Valerie Magalong; John Pintar; Brigitte L Kieffer; Alexander Z Harris; Jonathan A Javitch; René Hen; Katherine M Nautiyal
Journal:  Neuropsychopharmacology       Date:  2021-09-30       Impact factor: 8.294

3.  Effects of Tianeptine Treatment on Depression and Cognitive Function in Patients with Alzheimer's Disease: A 12-Month Retrospective Observational Study.

Authors:  José María García-Alberca; Esther Gris; Paz de la Guía; Silvia Mendoza
Journal:  J Alzheimers Dis       Date:  2022       Impact factor: 4.160
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.