BACKGROUND AND OBJECTIVE: To know the frequency of nosocomial infection (NI) in surgical hip fracture patients and to analyze the risk factors that favor the NI development, especially its relationship with allogeneic blood transfusion (ABT) and intravenous iron administration. PATIENTS AND METHOD: Unicenter prospective observational study of all hip fracture surgery patients during 8 months. The demographic, clinical and hematimetric differences between the infected and not infected patients were described. A logistic regression analysis was made to know the variables that predicted NI development. RESULTS: 26.1% of all 286 patients studied developed NI, urinary infection being the most frequent. The existence of lower hemoglobin or ferritin levels at admission, as well as increased values in ASA (American Society of Anesthesiologists) scale were associated with a greater risk of NI development. ABT and the number of red blood cell units transfused were also associated with an increase of the NI risk. No relationship between intravenous iron administration and NI was found. CONCLUSIONS: Lower haemoglobin and ferritin levels and ABT are associated with an increasing NI risk in surgical hip fracture patients. Thus, in order to decrease the frequency of NI in surgical patients, the development of blood saving protocols including intravenous iron administration would be recommendable.
BACKGROUND AND OBJECTIVE: To know the frequency of nosocomial infection (NI) in surgical hip fracturepatients and to analyze the risk factors that favor the NI development, especially its relationship with allogeneic blood transfusion (ABT) and intravenous iron administration. PATIENTS AND METHOD: Unicenter prospective observational study of all hip fracture surgery patients during 8 months. The demographic, clinical and hematimetric differences between the infected and not infected patients were described. A logistic regression analysis was made to know the variables that predicted NI development. RESULTS: 26.1% of all 286 patients studied developed NI, urinary infection being the most frequent. The existence of lower hemoglobin or ferritin levels at admission, as well as increased values in ASA (American Society of Anesthesiologists) scale were associated with a greater risk of NI development. ABT and the number of red blood cell units transfused were also associated with an increase of the NI risk. No relationship between intravenous iron administration and NI was found. CONCLUSIONS: Lower haemoglobin and ferritin levels and ABT are associated with an increasing NI risk in surgical hip fracturepatients. Thus, in order to decrease the frequency of NI in surgical patients, the development of blood saving protocols including intravenous iron administration would be recommendable.
Authors: Alexander B Benson; James R Burton; Gregory L Austin; Scott W Biggins; Michael A Zimmerman; Igal Kam; Susan Mandell; Christopher C Silliman; Hugo Rosen; Marc Moss Journal: Liver Transpl Date: 2011-02 Impact factor: 5.799
Authors: Santiago R Leal-Noval; Manuel Muñoz; Marisol Asuero; Enric Contreras; José A García-Erce; Juan V Llau; Victoria Moral; José A Páramo; Manuel Quintana Journal: Blood Transfus Date: 2013-06-17 Impact factor: 3.443
Authors: G S Tansarli; D E Karageorgopoulos; A Kapaskelis; I Gkegkes; M E Falagas Journal: Eur J Clin Microbiol Infect Dis Date: 2013-04-18 Impact factor: 3.267