Literature DB >> 19084441

Spontaneous resolution in patients with congenital Brown syndrome.

Emma Dawson1, John Barry, John Lee.   

Abstract

INTRODUCTION: Brown syndrome is characterized by a restriction of active and passive elevation in adduction. It can be congenital, acquired, intermittent, or constant. Spontaneous improvement has been reported in all types but is less common in congenital and constant cases.
METHODS: A retrospective review of patients seen between 1992 and 2002 was conducted at our tertiary referral center of all new referrals with a diagnosis of constant congenital Brown syndrome that was previously untreated.
RESULTS: Thirty-two patients were identified (22 female and 10 male patients), with an age range at referral of between 1 and 14 years. The right eye was affected in 14 patients, and 3 patients had bilateral Brown syndrome. Twenty-nine (91%) demonstrated binocular vision. Nineteen patients had an abnormal head posture. Twenty-four (75%) patients had some improvement in their ocular movements without any intervention. The best improvement was from a -3 limitation to full movement. Of 6 patients with a "click," 5 improved. Pain was a problem in 10 patients, 8 of whom improved. Diplopia was a symptom in 13 patients, of whom 11 improved. The final review ranged from 6 months to 9.5 years after the first visit. Five patients who had no spontaneous improvement underwent surgery and obtained improvement.
CONCLUSIONS: Spontaneous improvement occurred in 75% of patients. Our management is to be cautious with treatment and adopt an observational approach with these patients.

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Mesh:

Year:  2008        PMID: 19084441     DOI: 10.1016/j.jaapos.2008.09.007

Source DB:  PubMed          Journal:  J AAPOS        ISSN: 1091-8531            Impact factor:   1.220


  6 in total

1.  Late spontaneous resolution of congenital Brown syndrome.

Authors:  Scott R Lambert
Journal:  J AAPOS       Date:  2010-07-16       Impact factor: 1.220

2.  A Case Report of Progressive Brown Syndrome?

Authors:  A Coughlan; G E Arblaster; J P Burke
Journal:  Br Ir Orthopt J       Date:  2018-05-10

Review 3.  Fourth cranial nerve palsy and Brown syndrome: two interrelated congenital cranial dysinnervation disorders?

Authors:  Pierre-François Kaeser; Michael C Brodsky
Journal:  Curr Neurol Neurosci Rep       Date:  2013-06       Impact factor: 5.081

Review 4.  Ocular Abnormal Head Posture: A Literature Review.

Authors:  Mohamad Reza Akbari; Masoud Khorrami-Nejad; Haleh Kangari; Alireza Akbarzadeh Baghban; Mehdi Ranjbar Pazouki
Journal:  J Curr Ophthalmol       Date:  2022-01-06

5.  Hypertropia following Spontaneous Resolution of Brown's Syndrome.

Authors:  Jerrod S Kent; Inas Makar
Journal:  Case Rep Ophthalmol       Date:  2012-07-24

6.  The rate of superior oblique surgery in children and adolescents with Brown syndrome according to claims data.

Authors:  Hwan Heo; Scott R Lambert
Journal:  J AAPOS       Date:  2021-07-10       Impact factor: 1.325

  6 in total

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