Literature DB >> 19082806

Progress in research on the anti-tumor effect of artesunate.

Rong-rong HE1, Huai-jun ZHOU.   

Abstract

It has been found in recent years that Artesunate (Art), a water soluble derivative of arteannuin, mainly previously used for its anti-malarial activity, has some other effects, e.g. it could act as an anti-tumor agent by way of inducing cell apoptosis, antagonizing angiogenesis, reversing immunosuppression of tumor cells, etc. More and more attention is being paid to the anti-tumor effects of Art. Such progress is reviewed in this paper.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 19082806     DOI: 10.1007/s11655-008-0312-0

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  13 in total

1.  Transforming growth factor (TGF)-beta in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells.

Authors:  Eun-Sook Kim; Mi-Sung Kim; Aree Moon
Journal:  Cytokine       Date:  2005-01-21       Impact factor: 3.861

2.  The anti-malarial artesunate is also active against cancer.

Authors:  T Efferth; H Dunstan; A Sauerbrey; H Miyachi; C R Chitambar
Journal:  Int J Oncol       Date:  2001-04       Impact factor: 5.650

3.  Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells.

Authors:  Jun Lee; Hui-Jun Zhou; Xiu-Hua Wu
Journal:  Cancer Chemother Pharmacol       Date:  2005-08-02       Impact factor: 3.333

4.  Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-beta 1 and restores the lymphokine-activated killing activity.

Authors:  Ya-Wen Hsiao; Kuang-Wen Liao; Shao-Wen Hung; Rea-Min Chu
Journal:  J Immunol       Date:  2004-02-01       Impact factor: 5.422

5.  Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

Authors:  Paul C H Li; Elena Lam; Wynand P Roos; Malgorzata Z Zdzienicka; Bernd Kaina; Thomas Efferth
Journal:  Cancer Res       Date:  2008-06-01       Impact factor: 12.701

6.  Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells.

Authors:  Hui-Jun Zhou; Wei-Qin Wang; Guo-Dong Wu; Jun Lee; Ao Li
Journal:  Vascul Pharmacol       Date:  2007-05-24       Impact factor: 5.773

7.  Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway.

Authors:  Lin-Na Li; Hua-Dong Zhang; Shou-Jun Yuan; Zeng-Yue Tian; Lin Wang; Zhi-Xian Sun
Journal:  Int J Cancer       Date:  2007-09-15       Impact factor: 7.396

8.  [Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial].

Authors:  Zhu-Yi Zhang; Shi-Qing Yu; Li-Yun Miao; Xiao-Ying Huang; Xiao-Ping Zhang; Yu-Ping Zhu; Xiao-Hong Xia; Dan-Qi Li
Journal:  Zhong Xi Yi Jie He Xue Bao       Date:  2008-02

9.  Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate.

Authors:  Gerhard Kelter; Daniel Steinbach; Venkata Badireenath Konkimalla; Tsuyoshi Tahara; Shigeru Taketani; Heinz-Herbert Fiebig; Thomas Efferth
Journal:  PLoS One       Date:  2007-08-29       Impact factor: 3.240

10.  Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells.

Authors:  Thomas Efferth; Marco Giaisi; Annette Merling; Peter H Krammer; Min Li-Weber
Journal:  PLoS One       Date:  2007-08-01       Impact factor: 3.240

View more
  6 in total

1.  Artesunate protects pancreatic beta cells against cytokine-induced damage via SIRT1 inhibiting NF-κB activation.

Authors:  L Yu; J F Chen; X Shuai; Y Xu; Y Ding; J Zhang; W Yang; X Liang; D Su; C Yan
Journal:  J Endocrinol Invest       Date:  2015-06-11       Impact factor: 4.256

2.  Artesunate inhibiting angiogenesis induced by human myeloma RPMI8226 cells.

Authors:  Hao Chen; Liang Shi; Xiaoyang Yang; Shihui Li; Xiaoling Guo; Ling Pan
Journal:  Int J Hematol       Date:  2010-10-14       Impact factor: 2.490

3.  Effects of artesunate on the malignant biological behaviors of non-small cell lung cancer in human and its mechanism.

Authors:  Peng Hu; Chengyao Ni; Pen Teng
Journal:  Bioengineered       Date:  2022-03       Impact factor: 6.832

4.  Downregulation of HOTAIR Expression Mediated Anti-Metastatic Effect of Artesunate on Cervical Cancer by Inhibiting COX-2 Expression.

Authors:  Lixin Zhang; Hua Qian; Min Sha; Zhengyun Luan; Mei Lin; Donglan Yuan; Xiaokang Li; Junxing Huang; Lihua Ye
Journal:  PLoS One       Date:  2016-10-13       Impact factor: 3.240

5.  Effect of artesunate and relation with TGF-β1 and SMAD3 signaling on experimental hypertrophic scar model in rabbit ear.

Authors:  Xiaolin Nong; Girju Rajbanshi; Ling Chen; Jiaquan Li; Zhan Li; Taotao Liu; Shihai Chen; Gao Wei; Jushang Li
Journal:  Arch Dermatol Res       Date:  2019-08-09       Impact factor: 3.017

6.  [Effects of artesunate on the invasion of lung adenocarcinoma A549 cells and expression of ICAM-1 and MMP-9].

Authors:  Xianshan Chen; Kunyuan Han; Fengxia Chen; Congming Wu; Weiyi Huang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2013-11
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.