Literature DB >> 1908227

The human carbonic anhydrase I gene has two promoters with different tissue specificities.

H J Brady1, N Lowe, J C Sowden, M Edwards, P H Butterworth.   

Abstract

Primer extension and S1 nuclease analysis of human carbonic anhydrase I (HCA1) mRNA transcripts in erythroid and non-erythroid tissues show that the HCA1 gene has two promoters with different tissue specificities, separated by 36 kb of DNA. The promoter of the HCA1 gene which is active in non-erythroid tissue shows strong sequence similarity with a similar region in the mouse CA1 gene, but has two equally used transcription start sites.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1908227      PMCID： PMC1151332          DOI： 10.1042/bj2770903

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  15 in total

1.  Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.

Authors:  K A Jones; K R Yamamoto; R Tjian
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

2.  The mouse carbonic anhydrase I gene contains two tissue-specific promoters.

Authors:  P Fraser; P Cummings; P Curtis
Journal:  Mol Cell Biol       Date:  1989-08       Impact factor: 4.272

Review 3.  The carbonic anhydrases: widening perspectives on their evolution, expression and function.

Authors:  R E Tashian
Journal:  Bioessays       Date:  1989-06       Impact factor: 4.345

4.  Multiple GF-1 binding sites flank the erythroid specific transcription unit of the human carbonic anhydrase I gene.

Authors:  H J Brady; J C Sowden; M Edwards; N Lowe; P H Butterworth
Journal:  FEBS Lett       Date:  1989-11-06       Impact factor: 4.124

5.  The isoenzymes of carbonic anhydrase: tissue, subcellular distribution and functional significance, with particular reference to the intestinal tract.

Authors:  M J Carter; D S Parsons
Journal:  J Physiol       Date:  1971-05       Impact factor: 5.182

6.  Structure of the promoter region and tissue specificity of the human glycophorin C gene.

Authors:  C Le Van Kim; Y Colin; M T Mitjavila; M Clerget; A Dubart; M Nakazawa; W Vainchenker; J P Cartron
Journal:  J Biol Chem       Date:  1989-12-05       Impact factor: 5.157

7.  Distinct regions of Sp1 modulate DNA binding and transcriptional activation.

Authors:  J T Kadonaga; A J Courey; J Ladika; R Tjian
Journal:  Science       Date:  1988-12-16       Impact factor: 47.728

8.  Expression of the human carbonic anhydrase I gene is activated late in fetal erythroid development and regulated by stage-specific trans-acting factors.

Authors:  H J Brady; M Edwards; D C Linch; L Knott; J H Barlow; P H Butterworth
Journal:  Br J Haematol       Date:  1990-09       Impact factor: 6.998

9.  Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells.

Authors:  S F Tsai; D I Martin; L I Zon; A D D'Andrea; G G Wong; S H Orkin
Journal:  Nature       Date:  1989-06-08       Impact factor: 49.962

10.  Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

Authors:  S Chretien; A Dubart; D Beaupain; N Raich; B Grandchamp; J Rosa; M Goossens; P H Romeo
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205
View more
  2 in total

1.  Mutation creates an open reading frame within the 5' untranslated region of macaque erythrocyte carbonic anhydrase (CA) I mRNA that suppresses CA I expression and supports the scanning model for translation.

Authors:  N C Bergenhem; P J Venta; P J Hopkins; H J Kim; R E Tashian
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-15       Impact factor: 11.205

2.  Erythroid expression and DNAaseI-hypersensitive sites of the carbonic anhydrase 1 gene.

Authors:  J Sowden; M Edwards; K Morrison; P H Butterworth; Y H Edwards
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.